3BES

Structure of a Poxvirus ifngbp/ifng Complex

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0000122	biological_process	negative regulation of transcription by RNA polymerase II
L	0001774	biological_process	microglial cell activation
L	0001819	biological_process	positive regulation of cytokine production
L	0002250	biological_process	adaptive immune response
L	0002281	biological_process	macrophage activation involved in immune response
L	0005125	molecular_function	cytokine activity
L	0005133	molecular_function	type II interferon receptor binding
L	0005515	molecular_function	protein binding
L	0005576	cellular_component	extracellular region
L	0005615	cellular_component	extracellular space
L	0006915	biological_process	apoptotic process
L	0006955	biological_process	immune response
L	0006959	biological_process	humoral immune response
L	0007166	biological_process	cell surface receptor signaling pathway
L	0007259	biological_process	cell surface receptor signaling pathway via JAK-STAT
L	0008284	biological_process	positive regulation of cell population proliferation
L	0009615	biological_process	response to virus
L	0010508	biological_process	positive regulation of autophagy
L	0010628	biological_process	positive regulation of gene expression
L	0010629	biological_process	negative regulation of gene expression
L	0010634	biological_process	positive regulation of epithelial cell migration
L	0030225	biological_process	macrophage differentiation
L	0030857	biological_process	negative regulation of epithelial cell differentiation
L	0031334	biological_process	positive regulation of protein-containing complex assembly
L	0032700	biological_process	negative regulation of interleukin-17 production
L	0032722	biological_process	positive regulation of chemokine production
L	0032731	biological_process	positive regulation of interleukin-1 beta production
L	0032735	biological_process	positive regulation of interleukin-12 production
L	0032747	biological_process	positive regulation of interleukin-23 production
L	0032755	biological_process	positive regulation of interleukin-6 production
L	0032760	biological_process	positive regulation of tumor necrosis factor production
L	0032834	biological_process	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
L	0033141	biological_process	positive regulation of peptidyl-serine phosphorylation of STAT protein
L	0034393	biological_process	positive regulation of smooth muscle cell apoptotic process
L	0038196	biological_process	type III interferon-mediated signaling pathway
L	0042307	biological_process	positive regulation of protein import into nucleus
L	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
L	0045348	biological_process	positive regulation of MHC class II biosynthetic process
L	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
L	0045672	biological_process	positive regulation of osteoclast differentiation
L	0045821	biological_process	positive regulation of glycolytic process
L	0045892	biological_process	negative regulation of DNA-templated transcription
L	0048143	biological_process	astrocyte activation
L	0048662	biological_process	negative regulation of smooth muscle cell proliferation
L	0050729	biological_process	positive regulation of inflammatory response
L	0050766	biological_process	positive regulation of phagocytosis
L	0050769	biological_process	positive regulation of neurogenesis
L	0050796	biological_process	regulation of insulin secretion
L	0051044	biological_process	positive regulation of membrane protein ectodomain proteolysis
L	0051173	biological_process	obsolete positive regulation of nitrogen compound metabolic process
L	0051607	biological_process	defense response to virus
L	0051712	biological_process	positive regulation of killing of cells of another organism
L	0051770	biological_process	positive regulation of nitric-oxide synthase biosynthetic process
L	0060333	biological_process	type II interferon-mediated signaling pathway
L	0060550	biological_process	positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity
L	0060552	biological_process	positive regulation of fructose 1,6-bisphosphate metabolic process
L	0060557	biological_process	positive regulation of vitamin D biosynthetic process
L	0060559	biological_process	positive regulation of calcidiol 1-monooxygenase activity
L	0071902	biological_process	positive regulation of protein serine/threonine kinase activity
L	0090312	biological_process	positive regulation of protein deacetylation
L	0097191	biological_process	extrinsic apoptotic signaling pathway
L	0098586	biological_process	cellular response to virus
L	0150076	biological_process	neuroinflammatory response
L	1900222	biological_process	negative regulation of amyloid-beta clearance
L	1901857	biological_process	positive regulation of cellular respiration
L	1902004	biological_process	positive regulation of amyloid-beta formation
L	1902948	biological_process	negative regulation of tau-protein kinase activity
L	1903078	biological_process	positive regulation of protein localization to plasma membrane
L	1903543	biological_process	positive regulation of exosomal secretion
L	1904440	biological_process	positive regulation of iron ion import across plasma membrane
L	1904783	biological_process	positive regulation of NMDA glutamate receptor activity
L	1904798	biological_process	positive regulation of core promoter binding
L	2000273	biological_process	positive regulation of signaling receptor activity
L	2000309	biological_process	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
R	0004896	molecular_function	cytokine receptor activity
R	0005515	molecular_function	protein binding
R	0042802	molecular_function	identical protein binding
R	0060333	biological_process	type II interferon-mediated signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:3109913, ECO:0000269|PubMed:6427223

Chain	Residue	Details
L	GLN1

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site_id	SWS_FT_FI2
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:6427223

Chain	Residue	Details
L	ASN25

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; in dimeric form => ECO:0000269|PubMed:6427223

Chain	Residue	Details
L	ASN97

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