3BE0
The Role of Asn 242 in P450cin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| A | 0020037 | molecular_function | heme binding |
| A | 0046232 | biological_process | carbazole catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0055114 | biological_process | obsolete oxidation-reduction process |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| B | 0020037 | molecular_function | heme binding |
| B | 0046232 | biological_process | carbazole catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0055114 | biological_process | obsolete oxidation-reduction process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM A 450 |
| Chain | Residue |
| A | ASN73 |
| A | THR243 |
| A | ALA285 |
| A | ARG289 |
| A | SER339 |
| A | LEU340 |
| A | ILE344 |
| A | HIS345 |
| A | ARG346 |
| A | CYS347 |
| A | LEU348 |
| A | MET90 |
| A | GLY349 |
| A | LEU352 |
| A | ILE353 |
| A | CNL500 |
| A | HIS98 |
| A | ARG102 |
| A | PHE109 |
| A | ILE234 |
| A | GLY238 |
| A | GLY239 |
| A | ALA242 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CNL A 500 |
| Chain | Residue |
| A | THR77 |
| A | TYR81 |
| A | HEM450 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM B 450 |
| Chain | Residue |
| B | ILE65 |
| B | MET90 |
| B | ALA91 |
| B | HIS98 |
| B | ARG102 |
| B | PHE109 |
| B | ILE234 |
| B | GLY238 |
| B | GLY239 |
| B | ALA242 |
| B | THR243 |
| B | ARG289 |
| B | SER339 |
| B | LEU340 |
| B | GLY341 |
| B | ILE344 |
| B | HIS345 |
| B | ARG346 |
| B | CYS347 |
| B | LEU348 |
| B | GLY349 |
| B | LEU352 |
| B | ILE353 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CNL B 500 |
| Chain | Residue |
| B | ALA91 |
| B | VAL287 |
| B | VAL386 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15260491","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18270198","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22775403","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15260491","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Controls regioselective substrate oxidation"} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1akd |
| Chain | Residue | Details |
| A | ALA242 | |
| A | ASP241 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1akd |
| Chain | Residue | Details |
| B | ALA242 | |
| B | ASP241 |
