Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003911 | molecular_function | DNA ligase (NAD+) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 402 |
| Chain | Residue |
| A | LEU124 |
| A | ALA125 |
| A | ARG141 |
| A | HOH527 |
| A | HOH560 |
| A | HOH567 |
| A | HOH641 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 403 |
| Chain | Residue |
| A | ARG137 |
| A | HOH522 |
| A | HOH695 |
| A | HOH733 |
| A | PRO81 |
| A | ARG129 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 404 |
| Chain | Residue |
| A | ARG190 |
| A | GLN195 |
| A | GLN211 |
| A | ARG220 |
| A | HOH556 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE NMN A 401 |
| Chain | Residue |
| A | TYR25 |
| A | TYR29 |
| A | TYR30 |
| A | VAL37 |
| A | ASP39 |
| A | TYR42 |
| A | ASP43 |
| A | ARG158 |
| A | HOH507 |
| A | HOH593 |
| A | HOH612 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 3B8 A 501 |
| Chain | Residue |
| A | TYR87 |
| A | LEU89 |
| A | GLU118 |
| A | LEU119 |
| A | LYS120 |
| A | ILE121 |
| A | ARG141 |
| A | GLU175 |
| A | TYR227 |
| A | LYS291 |
| A | PRO308 |
| A | TRP310 |
Functional Information from PROSITE/UniProt
| site_id | PS01055 |
| Number of Residues | 30 |
| Details | DNA_LIGASE_N1 NAD-dependent DNA ligase signature 1. KIDGLAislrYenGvFvrgaTRGDGtvGEN |
| Chain | Residue | Details |
| A | LYS120-ASN149 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"N6-AMP-lysine intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_01588","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01588","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15296738","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1b04 |
| Chain | Residue | Details |
| A | LYS120 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1b04 |
| Chain | Residue | Details |
| A | LYS120 | |
| A | LYS315 | |
| A | ASP122 | |
| A | ARG202 | |
