3B6A
Crystal structure of the Streptomyces coelicolor TetR family protein ActR in complex with actinorhodin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| A | 0046677 | biological_process | response to antibiotic |
| B | 0003677 | molecular_function | DNA binding |
| B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| B | 0046677 | biological_process | response to antibiotic |
| C | 0003677 | molecular_function | DNA binding |
| C | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| C | 0046677 | biological_process | response to antibiotic |
| D | 0003677 | molecular_function | DNA binding |
| D | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| D | 0046677 | biological_process | response to antibiotic |
| E | 0003677 | molecular_function | DNA binding |
| E | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| E | 0046677 | biological_process | response to antibiotic |
| F | 0003677 | molecular_function | DNA binding |
| F | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| F | 0046677 | biological_process | response to antibiotic |
| G | 0003677 | molecular_function | DNA binding |
| G | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| G | 0046677 | biological_process | response to antibiotic |
| H | 0003677 | molecular_function | DNA binding |
| H | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| H | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ZCT A 1 |
| Chain | Residue |
| A | LEU87 |
| A | VAL137 |
| A | GLY138 |
| A | MET139 |
| A | ASP161 |
| A | SER164 |
| A | VAL90 |
| A | VAL92 |
| A | LEU111 |
| A | ALA125 |
| A | ILE126 |
| A | PRO130 |
| A | ASN134 |
| A | GLY135 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ZCT B 1 |
| Chain | Residue |
| A | GLU173 |
| B | LEU87 |
| B | VAL90 |
| B | VAL92 |
| B | LEU111 |
| B | ALA125 |
| B | ILE126 |
| B | ARG128 |
| B | PRO130 |
| B | ASN134 |
| B | GLY135 |
| B | GLY138 |
| B | MET139 |
| B | ASP161 |
| B | SER164 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ZCT C 1 |
| Chain | Residue |
| C | LEU87 |
| C | VAL90 |
| C | VAL92 |
| C | LEU111 |
| C | ALA125 |
| C | ILE126 |
| C | PRO130 |
| C | GLY138 |
| C | THR142 |
| C | SER164 |
| C | THR168 |
| D | LEU172 |
| D | GLU173 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ZCT D 1 |
| Chain | Residue |
| C | GLU173 |
| D | LEU87 |
| D | VAL90 |
| D | VAL92 |
| D | LEU111 |
| D | ALA125 |
| D | ILE126 |
| D | ARG128 |
| D | PRO130 |
| D | ASN134 |
| D | GLY135 |
| D | GLY138 |
| D | MET139 |
| D | ASP161 |
| D | SER164 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ZCT E 1 |
| Chain | Residue |
| E | LEU87 |
| E | VAL90 |
| E | GLU91 |
| E | VAL92 |
| E | LEU111 |
| E | ALA125 |
| E | ILE126 |
| E | ARG128 |
| E | PRO130 |
| E | ASN134 |
| E | GLY135 |
| E | GLY138 |
| E | ASP161 |
| E | SER164 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ZCT F 1 |
| Chain | Residue |
| F | LEU87 |
| F | VAL90 |
| F | GLU91 |
| F | VAL92 |
| F | ALA125 |
| F | ILE126 |
| F | ARG128 |
| F | PRO130 |
| F | ASN134 |
| F | GLY135 |
| F | GLY138 |
| F | MET139 |
| F | ARG141 |
| F | SER164 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ZCT G 1 |
| Chain | Residue |
| G | LEU87 |
| G | VAL90 |
| G | VAL92 |
| G | LEU111 |
| G | ALA125 |
| G | ILE126 |
| G | PRO130 |
| G | ASN134 |
| G | GLY135 |
| G | VAL137 |
| G | GLY138 |
| G | MET139 |
| G | ASP161 |
| G | SER164 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ZCT H 1 |
| Chain | Residue |
| H | LEU87 |
| H | VAL90 |
| H | VAL92 |
| H | LEU111 |
| H | ALA125 |
| H | ARG128 |
| H | PRO130 |
| H | ASN134 |
| H | GLY135 |
| H | GLY138 |
| H | MET139 |
| H | SER164 |
