3B60
Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP, higher resolution form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006869 | biological_process | lipid transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0034040 | molecular_function | ATPase-coupled lipid transmembrane transporter activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0140359 | molecular_function | ABC-type transporter activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006869 | biological_process | lipid transport |
| B | 0016020 | cellular_component | membrane |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0034040 | molecular_function | ATPase-coupled lipid transmembrane transporter activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0055085 | biological_process | transmembrane transport |
| B | 0140359 | molecular_function | ABC-type transporter activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006869 | biological_process | lipid transport |
| C | 0016020 | cellular_component | membrane |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0034040 | molecular_function | ATPase-coupled lipid transmembrane transporter activity |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0055085 | biological_process | transmembrane transport |
| C | 0140359 | molecular_function | ABC-type transporter activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0006869 | biological_process | lipid transport |
| D | 0016020 | cellular_component | membrane |
| D | 0016887 | molecular_function | ATP hydrolysis activity |
| D | 0034040 | molecular_function | ATPase-coupled lipid transmembrane transporter activity |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0055085 | biological_process | transmembrane transport |
| D | 0140359 | molecular_function | ABC-type transporter activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ANP A 5001 |
| Chain | Residue |
| A | TYR351 |
| B | LEU480 |
| B | SER482 |
| B | GLY484 |
| B | GLN485 |
| A | SER378 |
| A | GLY379 |
| A | SER380 |
| A | GLY381 |
| A | LYS382 |
| A | SER383 |
| A | THR384 |
| A | HIS537 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ANP B 5002 |
| Chain | Residue |
| A | LEU480 |
| A | SER482 |
| A | GLY484 |
| A | GLN485 |
| B | TYR351 |
| B | SER378 |
| B | GLY379 |
| B | SER380 |
| B | GLY381 |
| B | LYS382 |
| B | SER383 |
| B | THR384 |
| B | HIS537 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ANP C 5003 |
| Chain | Residue |
| C | TYR351 |
| C | SER378 |
| C | GLY379 |
| C | SER380 |
| C | GLY381 |
| C | LYS382 |
| C | SER383 |
| C | THR384 |
| C | HIS537 |
| D | LEU480 |
| D | LEU481 |
| D | SER482 |
| D | GLY483 |
| D | GLY484 |
| D | GLN485 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ANP D 5004 |
| Chain | Residue |
| C | LEU480 |
| C | SER482 |
| C | GLY483 |
| C | GLY484 |
| C | GLN485 |
| D | TYR351 |
| D | SER378 |
| D | GLY379 |
| D | SER380 |
| D | GLY381 |
| D | LYS382 |
| D | SER383 |
| D | THR384 |
| D | HIS537 |
Functional Information from PROSITE/UniProt
| site_id | PS00211 |
| Number of Residues | 15 |
| Details | ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQRQRIAIARAL |
| Chain | Residue | Details |
| A | LEU481-LEU495 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 400 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"HAMAP-Rule","id":"MF_01703","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1128 |
| Details | Domain: {"description":"ABC transmembrane type-1","evidences":[{"source":"HAMAP-Rule","id":"MF_01703","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 944 |
| Details | Domain: {"description":"ABC transporter","evidences":[{"source":"HAMAP-Rule","id":"MF_01703","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01703","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
