3B5Y

Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006869	biological_process	lipid transport
A	0016020	cellular_component	membrane
A	0016887	molecular_function	ATP hydrolysis activity
A	0034040	molecular_function	ATPase-coupled lipid transmembrane transporter activity
A	0042802	molecular_function	identical protein binding
A	0055085	biological_process	transmembrane transport
A	0140359	molecular_function	ABC-type transporter activity
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006869	biological_process	lipid transport
B	0016020	cellular_component	membrane
B	0016887	molecular_function	ATP hydrolysis activity
B	0034040	molecular_function	ATPase-coupled lipid transmembrane transporter activity
B	0042802	molecular_function	identical protein binding
B	0055085	biological_process	transmembrane transport
B	0140359	molecular_function	ABC-type transporter activity
C	0000166	molecular_function	nucleotide binding
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0006869	biological_process	lipid transport
C	0016020	cellular_component	membrane
C	0016887	molecular_function	ATP hydrolysis activity
C	0034040	molecular_function	ATPase-coupled lipid transmembrane transporter activity
C	0042802	molecular_function	identical protein binding
C	0055085	biological_process	transmembrane transport
C	0140359	molecular_function	ABC-type transporter activity
D	0000166	molecular_function	nucleotide binding
D	0005524	molecular_function	ATP binding
D	0005886	cellular_component	plasma membrane
D	0006869	biological_process	lipid transport
D	0016020	cellular_component	membrane
D	0016887	molecular_function	ATP hydrolysis activity
D	0034040	molecular_function	ATPase-coupled lipid transmembrane transporter activity
D	0042802	molecular_function	identical protein binding
D	0055085	biological_process	transmembrane transport
D	0140359	molecular_function	ABC-type transporter activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ANP B 5001

Chain	Residue
A	SER378
A	GLY379
B	LEU480
B	SER482

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ANP A 5002

Chain	Residue
A	LEU480
A	SER482
B	SER378
B	THR384

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ANP D 5003

Chain	Residue
C	SER383
C	THR384
D	LEU480
D	SER482
C	SER378

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ANP C 5004

Chain	Residue
C	LEU480
C	SER482
D	SER378
D	SER383
D	THR384

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Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQRQRIAIARAL

Chain	Residue	Details
A	LEU481-LEU495

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	400
Details	TRANSMEM: Helical => ECO:0000255|HAMAP-Rule:MF_01703

Chain	Residue	Details
A	LEU64-ILE84
A	ILE153-VAL173
A	VAL275-MET295
B	LEU16-LEU36
B	LEU64-ILE84
B	ILE153-VAL173
B	PRO253-PRO273
B	VAL275-MET295
C	LEU16-LEU36
C	LEU64-ILE84
C	ILE153-VAL173
C	PRO253-PRO273
C	VAL275-MET295
D	LEU16-LEU36
D	LEU64-ILE84
D	ILE153-VAL173
D	PRO253-PRO273
D	VAL275-MET295
A	LEU16-LEU36
A	PRO253-PRO273

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01703

Chain	Residue	Details
B	GLY376
C	GLY376
A	GLY376
D	GLY376

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