3B4Y
FGD1 (Rv0407) from Mycobacterium tuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0045454 | biological_process | cell redox homeostasis |
| A | 0052749 | molecular_function | glucose-6-phosphate dehydrogenase (coenzyme F420) activity |
| A | 0070967 | molecular_function | coenzyme F420 binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0045454 | biological_process | cell redox homeostasis |
| B | 0052749 | molecular_function | glucose-6-phosphate dehydrogenase (coenzyme F420) activity |
| B | 0070967 | molecular_function | coenzyme F420 binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE F42 A 338 |
| Chain | Residue |
| A | SER38 |
| A | GLU109 |
| A | ASN112 |
| A | PHE125 |
| A | ALA175 |
| A | ALA176 |
| A | GLY177 |
| A | GLY178 |
| A | PRO179 |
| A | ALA180 |
| A | VAL181 |
| A | ASP39 |
| A | THR195 |
| A | GLU230 |
| A | HIS260 |
| A | FLC337 |
| A | HOH339 |
| A | HOH341 |
| A | HOH368 |
| A | HOH402 |
| A | HIS40 |
| A | SER73 |
| A | VAL74 |
| A | THR76 |
| A | GLY106 |
| A | THR107 |
| A | GLY108 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE FLC A 337 |
| Chain | Residue |
| A | TRP44 |
| A | GLU109 |
| A | THR195 |
| A | LYS198 |
| A | LYS232 |
| A | LEU252 |
| A | LYS259 |
| A | HIS260 |
| A | ARG283 |
| A | F42338 |
| A | HOH368 |
| A | HOH411 |
| A | HOH424 |
| site_id | AC3 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE F42 B 338 |
| Chain | Residue |
| B | SER38 |
| B | ASP39 |
| B | HIS40 |
| B | SER73 |
| B | VAL74 |
| B | THR76 |
| B | GLY106 |
| B | THR107 |
| B | GLY108 |
| B | GLU109 |
| B | ASN112 |
| B | PHE125 |
| B | ALA175 |
| B | ALA176 |
| B | GLY177 |
| B | GLY178 |
| B | PRO179 |
| B | ALA180 |
| B | VAL181 |
| B | THR195 |
| B | GLU230 |
| B | HIS260 |
| B | FLC337 |
| B | HOH345 |
| B | HOH351 |
| B | HOH355 |
| B | HOH358 |
| B | HOH360 |
| B | HOH425 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE FLC B 337 |
| Chain | Residue |
| B | TRP44 |
| B | GLU109 |
| B | THR195 |
| B | LYS198 |
| B | LYS232 |
| B | LEU252 |
| B | LYS259 |
| B | HIS260 |
| B | ARG283 |
| B | F42338 |
| B | HOH346 |
| B | HOH358 |
| B | HOH403 |
Functional Information from PROSITE/UniProt
| site_id | PS00683 |
| Number of Residues | 11 |
| Details | RHODANESE_2 Rhodanese C-terminal signature. AtgYEGAWpEF |
| Chain | Residue | Details |
| A | ALA115-PHE125 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"18434308","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"18434308","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18434308","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3B4Y","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18434308","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1rhc |
| Chain | Residue | Details |
| A | GLU109 | |
| A | TRP44 | |
| A | HIS40 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1rhc |
| Chain | Residue | Details |
| B | GLU109 | |
| B | TRP44 | |
| B | HIS40 |
