3B2L

Iodide derivative of human LFABP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003682	molecular_function	chromatin binding
A	0005324	molecular_function	long-chain fatty acid transmembrane transporter activity
A	0005504	molecular_function	fatty acid binding
A	0005515	molecular_function	protein binding
A	0005543	molecular_function	phospholipid binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005782	cellular_component	peroxisomal matrix
A	0005829	cellular_component	cytosol
A	0008289	molecular_function	lipid binding
A	0015908	biological_process	fatty acid transport
A	0015909	biological_process	long-chain fatty acid transport
A	0016209	molecular_function	antioxidant activity
A	0032000	biological_process	positive regulation of fatty acid beta-oxidation
A	0032052	molecular_function	bile acid binding
A	0032991	cellular_component	protein-containing complex
A	0033552	biological_process	response to vitamin B3
A	0043066	biological_process	negative regulation of apoptotic process
A	0043154	biological_process	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
A	0045179	cellular_component	apical cortex
A	0050892	biological_process	intestinal absorption
A	0070062	cellular_component	extracellular exosome
A	0070301	biological_process	cellular response to hydrogen peroxide
A	0070538	molecular_function	oleic acid binding
A	0071456	biological_process	cellular response to hypoxia
A	0098869	biological_process	cellular oxidant detoxification
A	1901363	molecular_function	heterocyclic compound binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PLM A 150

Chain	Residue
A	SER39
A	PHE50
A	GLU72
A	PHE95
A	THR102
A	ILE109
A	ASN111
A	MET113
A	ARG122

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site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PLM A 151

Chain	Residue
A	PHE15
A	LEU28
A	ILE52
A	ALA54
A	GLY55
A	SER56
A	LYS57
A	MET74
A	ASN111
A	ARG122

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 130

Chain	Residue
A	MET74
A	IOD133

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site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 131

Chain	Residue
A	GLN12

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 132

Chain	Residue
A	GLU40
A	LYS49
A	THR51

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 133

Chain	Residue
A	THR73
A	IOD130

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site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 134

Chain	Residue
A	SER11
A	GLU13
A	ILE123

---

Functional Information from PROSITE/UniProt

site_id	PS00214
Number of Residues	18
Details	FABP Cytosolic fatty-acid binding proteins signature. GKYqLqsQeNFEaFMKAI

Chain	Residue	Details
A	GLY5-ILE22

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	SER11
A	SER56

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site_id	SWS_FT_FI2
Number of Residues	7
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P12710

Chain	Residue	Details
A	LYS31
A	LYS36
A	LYS46
A	LYS57
A	LYS78
A	LYS90
A	LYS121

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P02692

Chain	Residue	Details
A	SER39

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	THR51

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P12710

Chain	Residue	Details
A	SER100

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