3B2H

Iodide derivative of human LFABP at high resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003682	molecular_function	chromatin binding
A	0005504	molecular_function	fatty acid binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005782	cellular_component	peroxisomal matrix
A	0005829	cellular_component	cytosol
A	0008289	molecular_function	lipid binding
A	0015908	biological_process	fatty acid transport
A	0016209	molecular_function	antioxidant activity
A	0070062	cellular_component	extracellular exosome
A	0070301	biological_process	cellular response to hydrogen peroxide
A	0071456	biological_process	cellular response to hypoxia
A	0098869	biological_process	cellular oxidant detoxification
A	1990748	biological_process	cellular detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PLM A 150

Chain	Residue
A	SER39
A	HOH226
A	ASN61
A	GLU72
A	MET74
A	PHE95
A	SER100
A	THR102
A	ASN111
A	ARG122

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PLM A 151

Chain	Residue
A	PHE15
A	LEU28
A	GLY55
A	SER56
A	ASN111
A	MET113
A	ARG122

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 130

Chain	Residue
A	MET74
A	IOD134

---

site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 131

Chain	Residue
A	GLN12

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 132

Chain	Residue
A	GLU40
A	THR51

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 133

Chain	Residue
A	GLN10
A	ASN97
A	HOH350

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 134

Chain	Residue
A	THR73
A	LYS96
A	IOD130

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 135

Chain	Residue
A	SER11
A	GLU13
A	LYS121

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE IOD A 136

Chain	Residue
A	HIS47
A	VAL65
A	GLN84
A	LEU85
A	IOD138
A	HOH347

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE IOD A 138

Chain	Residue
A	PHE63
A	THR64
A	IOD136
A	HOH261
A	HOH266
A	HOH347

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IOD A 139

Chain	Residue
A	GLY116
A	ASP117
A	LYS125
A	ARG126

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IOD A 140

Chain	Residue
A	GLN8
A	GLN10
A	GLY76
A	HOH252

---

site_id	BC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 141

Chain	Residue
A	LYS96
A	HOH318

---

Functional Information from PROSITE/UniProt

site_id	PS00214
Number of Residues	18
Details	FABP Cytosolic fatty-acid binding proteins signature. GKYqLqsQeNFEaFMKAI

Chain	Residue	Details
A	GLY5-ILE22

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	7
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P12710","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P02692","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P12710","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---