3B2D
Crystal structure of human RP105/MD-1 complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001875 | molecular_function | lipopolysaccharide immune receptor activity |
| A | 0002322 | biological_process | B cell proliferation involved in immune response |
| A | 0002376 | biological_process | immune system process |
| A | 0005515 | molecular_function | protein binding |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005730 | cellular_component | nucleolus |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006954 | biological_process | inflammatory response |
| A | 0031663 | biological_process | lipopolysaccharide-mediated signaling pathway |
| A | 0031666 | biological_process | positive regulation of lipopolysaccharide-mediated signaling pathway |
| A | 0038023 | molecular_function | signaling receptor activity |
| A | 0042100 | biological_process | B cell proliferation |
| A | 0045087 | biological_process | innate immune response |
| A | 0071222 | biological_process | cellular response to lipopolysaccharide |
| A | 0072686 | cellular_component | mitotic spindle |
| B | 0001875 | molecular_function | lipopolysaccharide immune receptor activity |
| B | 0002322 | biological_process | B cell proliferation involved in immune response |
| B | 0002376 | biological_process | immune system process |
| B | 0005515 | molecular_function | protein binding |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0005730 | cellular_component | nucleolus |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006954 | biological_process | inflammatory response |
| B | 0031663 | biological_process | lipopolysaccharide-mediated signaling pathway |
| B | 0031666 | biological_process | positive regulation of lipopolysaccharide-mediated signaling pathway |
| B | 0038023 | molecular_function | signaling receptor activity |
| B | 0042100 | biological_process | B cell proliferation |
| B | 0045087 | biological_process | innate immune response |
| B | 0071222 | biological_process | cellular response to lipopolysaccharide |
| B | 0072686 | cellular_component | mitotic spindle |
| C | 0002376 | biological_process | immune system process |
| C | 0005515 | molecular_function | protein binding |
| C | 0005576 | cellular_component | extracellular region |
| C | 0006954 | biological_process | inflammatory response |
| C | 0006955 | biological_process | immune response |
| C | 0031663 | biological_process | lipopolysaccharide-mediated signaling pathway |
| C | 0031666 | biological_process | positive regulation of lipopolysaccharide-mediated signaling pathway |
| C | 0045087 | biological_process | innate immune response |
| D | 0002376 | biological_process | immune system process |
| D | 0005515 | molecular_function | protein binding |
| D | 0005576 | cellular_component | extracellular region |
| D | 0006954 | biological_process | inflammatory response |
| D | 0006955 | biological_process | immune response |
| D | 0031663 | biological_process | lipopolysaccharide-mediated signaling pathway |
| D | 0031666 | biological_process | positive regulation of lipopolysaccharide-mediated signaling pathway |
| D | 0045087 | biological_process | innate immune response |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Domain: {"description":"LRRNT"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"LRR 7"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 8"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 9"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 10"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"LRR 11"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"LRR 12"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 13"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 14"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"LRR 15"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"LRR 16"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"LRR 17"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI19 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"LRR 18"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI20 |
| Number of Residues | 36 |
| Details | Repeat: {"description":"LRR 19"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI21 |
| Number of Residues | 20 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI22 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI23 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"21959264","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
