3B1E
Crystal structure of betaC-S lyase from Streptococcus anginosus in complex with L-serine: alpha-Aminoacrylate form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0047804 | molecular_function | cysteine-S-conjugate beta-lyase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0047804 | molecular_function | cysteine-S-conjugate beta-lyase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0047804 | molecular_function | cysteine-S-conjugate beta-lyase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0047804 | molecular_function | cysteine-S-conjugate beta-lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE P1T A 401 |
| Chain | Residue |
| A | ILE34 |
| A | ILE201 |
| A | HIS202 |
| A | LYS234 |
| A | ARG365 |
| A | HOH815 |
| A | HOH853 |
| A | HOH903 |
| A | HOH923 |
| A | HOH930 |
| A | HOH946 |
| A | ALA35 |
| A | HOH971 |
| B | TYR60 |
| A | GLY93 |
| A | VAL94 |
| A | VAL95 |
| A | TYR119 |
| A | CYS167 |
| A | ASN171 |
| A | ASP199 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE EPE A 501 |
| Chain | Residue |
| A | TYR60 |
| A | GLU268 |
| A | HOH854 |
| A | HOH1188 |
| B | TYR18 |
| B | TRP33 |
| B | VAL95 |
| B | TYR119 |
| B | HOH980 |
| C | EPE502 |
| C | HOH972 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE EPE A 502 |
| Chain | Residue |
| A | PRO120 |
| A | PRO121 |
| A | ASP355 |
| A | HOH967 |
| A | HOH987 |
| A | HOH1012 |
| A | HOH1055 |
| A | HOH1064 |
| A | HOH1102 |
| B | EPE501 |
| D | ASP336 |
| D | ARG352 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EPE A 503 |
| Chain | Residue |
| A | ASP84 |
| A | LYS85 |
| A | GLU86 |
| A | HOH898 |
| C | GLN28 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 601 |
| Chain | Residue |
| A | SER358 |
| A | HOH839 |
| A | HOH1142 |
| A | HOH1218 |
| A | HOH1219 |
| site_id | AC6 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE P1T B 401 |
| Chain | Residue |
| A | TYR60 |
| B | ILE34 |
| B | ALA35 |
| B | GLY93 |
| B | VAL94 |
| B | VAL95 |
| B | PRO96 |
| B | TYR119 |
| B | CYS167 |
| B | ASN171 |
| B | ASP199 |
| B | ILE201 |
| B | HIS202 |
| B | LYS234 |
| B | ARG365 |
| B | HOH857 |
| B | HOH860 |
| B | HOH865 |
| B | HOH880 |
| B | HOH941 |
| B | HOH980 |
| B | HOH997 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EPE B 501 |
| Chain | Residue |
| A | TYR18 |
| A | TRP33 |
| A | VAL95 |
| A | TYR119 |
| A | EPE502 |
| A | HOH971 |
| A | HOH1064 |
| B | TYR60 |
| B | GLU268 |
| B | HOH845 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EPE B 502 |
| Chain | Residue |
| B | ASP84 |
| B | LYS85 |
| B | GLU86 |
| B | HOH948 |
| B | HOH1139 |
| D | GLN28 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 601 |
| Chain | Residue |
| B | SER358 |
| B | HOH943 |
| B | HOH953 |
| B | HOH958 |
| B | HOH1227 |
| B | HOH1237 |
| site_id | BC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE P1T C 401 |
| Chain | Residue |
| C | ALA35 |
| C | GLY93 |
| C | VAL94 |
| C | VAL95 |
| C | PRO96 |
| C | TYR119 |
| C | CYS167 |
| C | ASN171 |
| C | ASP199 |
| C | ILE201 |
| C | HIS202 |
| C | LYS234 |
| C | ARG365 |
| C | HOH803 |
| C | HOH844 |
| C | HOH867 |
| C | HOH886 |
| C | HOH899 |
| C | HOH1004 |
| C | HOH1067 |
| D | TYR60 |
| C | ILE34 |
| site_id | BC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE EPE C 501 |
| Chain | Residue |
| C | TYR60 |
| C | GLU268 |
| C | HOH832 |
| C | HOH1083 |
| C | HOH1115 |
| D | TYR18 |
| D | TRP33 |
| D | VAL95 |
| D | TYR119 |
| D | EPE502 |
| D | HOH859 |
| D | HOH1019 |
| site_id | BC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE EPE C 502 |
| Chain | Residue |
| A | EPE501 |
| B | PRO120 |
| B | PRO121 |
| B | ASP355 |
| B | HOH857 |
| B | HOH895 |
| B | HOH1055 |
| C | ASP336 |
| C | ARG352 |
| C | HOH972 |
| C | HOH1149 |
| site_id | BC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EPE C 503 |
| Chain | Residue |
| B | ASP336 |
| B | ARG352 |
| C | PRO120 |
| C | PRO121 |
| C | ASP355 |
| C | HOH984 |
| C | HOH1014 |
| C | HOH1085 |
| D | EPE501 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA C 601 |
| Chain | Residue |
| B | HOH1042 |
| C | SER358 |
| C | HOH925 |
| C | HOH1076 |
| C | HOH1156 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT C 701 |
| Chain | Residue |
| C | GLN47 |
| C | HIS50 |
| C | GLU54 |
| C | HOH926 |
| D | HIS50 |
| site_id | BC7 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE P1T D 401 |
| Chain | Residue |
| C | TYR60 |
| D | ILE34 |
| D | ALA35 |
| D | GLY93 |
| D | VAL94 |
| D | VAL95 |
| D | TYR119 |
| D | CYS167 |
| D | ASN171 |
| D | ASP199 |
| D | ILE201 |
| D | HIS202 |
| D | LYS234 |
| D | ARG365 |
| D | HOH849 |
| D | HOH859 |
| D | HOH865 |
| D | HOH887 |
| D | HOH905 |
| D | HOH908 |
| D | HOH996 |
| site_id | BC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EPE D 501 |
| Chain | Residue |
| C | TYR18 |
| C | TRP33 |
| C | VAL95 |
| C | TYR119 |
| C | EPE503 |
| C | HOH803 |
| C | HOH984 |
| D | TYR60 |
| D | GLU268 |
| D | HOH934 |
| site_id | BC9 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE EPE D 502 |
| Chain | Residue |
| A | PHE339 |
| A | THR340 |
| C | EPE501 |
| D | PRO120 |
| D | PRO121 |
| D | ASP355 |
| D | HOH865 |
| D | HOH907 |
| D | HOH935 |
| D | HOH1004 |
| D | HOH1019 |
| D | HOH1052 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EPE D 503 |
| Chain | Residue |
| D | ASP84 |
| D | LYS85 |
| D | GLU86 |
| D | HOH986 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA D 601 |
| Chain | Residue |
| D | SER358 |
| D | HOH851 |
| D | HOH976 |
| D | HOH1003 |
| D | HOH1154 |
| D | HOH1155 |
