3B1D

Crystal structure of betaC-S lyase from Streptococcus anginosus in complex with L-serine: External aldimine form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0009058	biological_process	biosynthetic process
A	0016829	molecular_function	lyase activity
A	0030170	molecular_function	pyridoxal phosphate binding
B	0003824	molecular_function	catalytic activity
B	0009058	biological_process	biosynthetic process
B	0016829	molecular_function	lyase activity
B	0030170	molecular_function	pyridoxal phosphate binding
C	0003824	molecular_function	catalytic activity
C	0009058	biological_process	biosynthetic process
C	0016829	molecular_function	lyase activity
C	0030170	molecular_function	pyridoxal phosphate binding
D	0003824	molecular_function	catalytic activity
D	0009058	biological_process	biosynthetic process
D	0016829	molecular_function	lyase activity
D	0030170	molecular_function	pyridoxal phosphate binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE PLP A 401

Chain	Residue
A	VAL94
A	HOH852
A	HOH960
A	HOH1064
B	TYR60
B	EPE601
A	VAL95
A	PRO96
A	TYR119
A	CYS167
A	ASN171
A	ASP199
A	ILE201
A	HIS202

---

site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE PLS A 501

Chain	Residue
A	ILE34
A	ALA35
A	GLY93
A	VAL94
A	VAL95
A	TYR119
A	CYS167
A	ASN171
A	ASP199
A	ILE201
A	HIS202
A	ARG365
A	HOH852
A	HOH927
A	HOH960
A	HOH1064
B	TYR60
B	EPE601

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE EPE A 601

Chain	Residue
A	TYR60
A	GLU268
A	HOH1041
B	TYR18
B	TRP33
B	TYR119
B	PLS501
B	HOH1184
B	HOH1201
C	EPE602

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EPE A 602

Chain	Residue
A	PRO120
A	PRO121
A	ASP355
A	HOH1035
A	HOH1079
B	EPE601
D	ASP336
D	ARG352

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EPE A 603

Chain	Residue
A	ASP84
A	LYS85
A	GLU86
A	HOH940
A	HOH1200
C	GLN28

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 701

Chain	Residue
A	SER358
A	HOH895
A	HOH970
A	HOH1025
A	HOH1037
A	HOH1157

---

site_id	AC7
Number of Residues	21
Details	BINDING SITE FOR RESIDUE PLS B 501

Chain	Residue
A	TYR60
A	EPE601
B	ILE34
B	ALA35
B	GLY93
B	VAL94
B	VAL95
B	PRO96
B	TYR119
B	CYS167
B	ASN171
B	ASP199
B	ILE201
B	HIS202
B	LYS234
B	ARG365
B	HOH848
B	HOH903
B	HOH961
B	HOH1184
B	HOH1201

---

site_id	AC8
Number of Residues	12
Details	BINDING SITE FOR RESIDUE EPE B 601

Chain	Residue
A	TYR18
A	TRP33
A	VAL95
A	TYR119
A	PLP401
A	PLS501
A	EPE602
A	HOH1064
A	HOH1177
B	TYR60
B	GLU268
B	HOH953

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EPE B 602

Chain	Residue
B	ASP84
B	LYS85
B	GLU86
B	HOH925

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA B 701

Chain	Residue
B	SER358
B	HOH939
B	HOH970
B	HOH1059
B	HOH1070
B	HOH1185

---

site_id	BC2
Number of Residues	14
Details	BINDING SITE FOR RESIDUE PLP C 401

Chain	Residue
C	VAL94
C	VAL95
C	PRO96
C	TYR119
C	CYS167
C	ASN171
C	ASP199
C	ILE201
C	HIS202
C	HOH852
C	HOH900
C	HOH1139
C	HOH1171
D	TYR60

---

site_id	BC3
Number of Residues	20
Details	BINDING SITE FOR RESIDUE PLS C 501

Chain	Residue
C	ILE34
C	ALA35
C	GLY93
C	VAL94
C	VAL95
C	TYR119
C	CYS167
C	ASN171
C	ASP199
C	ILE201
C	HIS202
C	ARG365
C	HOH852
C	HOH900
C	HOH911
C	HOH933
C	HOH1139
C	HOH1171
D	TYR60
D	EPE601

---

site_id	BC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE EPE C 601

Chain	Residue
C	TYR60
C	GLU268
C	HOH877
D	TYR18
D	TRP33
D	VAL95
D	TYR119
D	PLS501
D	EPE602
D	HOH1037
D	HOH1144

---

site_id	BC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EPE C 602

Chain	Residue
A	EPE601
B	PRO120
B	PRO121
B	HOH849
B	HOH927
B	HOH1100
B	HOH1201
C	HOH1040

---

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EPE C 603

Chain	Residue
C	PRO120
C	PRO121
C	HOH911
C	HOH1068
C	HOH1097
C	HOH1129
D	EPE601

---

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA C 701

Chain	Residue
C	SER358
C	HOH923
C	HOH949
C	HOH1058
C	HOH1114

---

site_id	BC8
Number of Residues	20
Details	BINDING SITE FOR RESIDUE PLS D 501

Chain	Residue
C	TYR60
C	EPE601
D	ILE34
D	ALA35
D	GLY93
D	VAL94
D	VAL95
D	TYR119
D	CYS167
D	ASN171
D	ASP199
D	ILE201
D	HIS202
D	LYS234
D	ARG365
D	HOH828
D	HOH851
D	HOH907
D	HOH1037
D	HOH1144

---

site_id	BC9
Number of Residues	12
Details	BINDING SITE FOR RESIDUE EPE D 601

Chain	Residue
C	TYR18
C	TRP33
C	VAL95
C	TYR119
C	PLS501
C	EPE603
C	HOH1097
C	HOH1129
C	HOH1139
D	TYR60
D	GLU268
D	HOH927

---

site_id	CC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE EPE D 602

Chain	Residue
A	ASP336
A	PHE339
C	EPE601
D	PRO120
D	PRO121
D	ASP355
D	HOH989
D	HOH1039
D	HOH1063
D	HOH1067
D	HOH1106
D	HOH1144

---

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EPE D 603

Chain	Residue
D	ASP84
D	LYS85
D	GLU86
D	HOH965

---

site_id	CC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA D 701

Chain	Residue
D	SER358
D	HOH827
D	HOH939
D	HOH964
D	HOH966
D	HOH1017

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