3B1D
Crystal structure of betaC-S lyase from Streptococcus anginosus in complex with L-serine: External aldimine form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0047804 | molecular_function | cysteine-S-conjugate beta-lyase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0047804 | molecular_function | cysteine-S-conjugate beta-lyase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0047804 | molecular_function | cysteine-S-conjugate beta-lyase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0047804 | molecular_function | cysteine-S-conjugate beta-lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PLP A 401 |
| Chain | Residue |
| A | VAL94 |
| A | HOH852 |
| A | HOH960 |
| A | HOH1064 |
| B | TYR60 |
| B | EPE601 |
| A | VAL95 |
| A | PRO96 |
| A | TYR119 |
| A | CYS167 |
| A | ASN171 |
| A | ASP199 |
| A | ILE201 |
| A | HIS202 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE PLS A 501 |
| Chain | Residue |
| A | ILE34 |
| A | ALA35 |
| A | GLY93 |
| A | VAL94 |
| A | VAL95 |
| A | TYR119 |
| A | CYS167 |
| A | ASN171 |
| A | ASP199 |
| A | ILE201 |
| A | HIS202 |
| A | ARG365 |
| A | HOH852 |
| A | HOH927 |
| A | HOH960 |
| A | HOH1064 |
| B | TYR60 |
| B | EPE601 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EPE A 601 |
| Chain | Residue |
| A | TYR60 |
| A | GLU268 |
| A | HOH1041 |
| B | TYR18 |
| B | TRP33 |
| B | TYR119 |
| B | PLS501 |
| B | HOH1184 |
| B | HOH1201 |
| C | EPE602 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EPE A 602 |
| Chain | Residue |
| A | PRO120 |
| A | PRO121 |
| A | ASP355 |
| A | HOH1035 |
| A | HOH1079 |
| B | EPE601 |
| D | ASP336 |
| D | ARG352 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EPE A 603 |
| Chain | Residue |
| A | ASP84 |
| A | LYS85 |
| A | GLU86 |
| A | HOH940 |
| A | HOH1200 |
| C | GLN28 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 701 |
| Chain | Residue |
| A | SER358 |
| A | HOH895 |
| A | HOH970 |
| A | HOH1025 |
| A | HOH1037 |
| A | HOH1157 |
| site_id | AC7 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE PLS B 501 |
| Chain | Residue |
| A | TYR60 |
| A | EPE601 |
| B | ILE34 |
| B | ALA35 |
| B | GLY93 |
| B | VAL94 |
| B | VAL95 |
| B | PRO96 |
| B | TYR119 |
| B | CYS167 |
| B | ASN171 |
| B | ASP199 |
| B | ILE201 |
| B | HIS202 |
| B | LYS234 |
| B | ARG365 |
| B | HOH848 |
| B | HOH903 |
| B | HOH961 |
| B | HOH1184 |
| B | HOH1201 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE EPE B 601 |
| Chain | Residue |
| A | TYR18 |
| A | TRP33 |
| A | VAL95 |
| A | TYR119 |
| A | PLP401 |
| A | PLS501 |
| A | EPE602 |
| A | HOH1064 |
| A | HOH1177 |
| B | TYR60 |
| B | GLU268 |
| B | HOH953 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EPE B 602 |
| Chain | Residue |
| B | ASP84 |
| B | LYS85 |
| B | GLU86 |
| B | HOH925 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 701 |
| Chain | Residue |
| B | SER358 |
| B | HOH939 |
| B | HOH970 |
| B | HOH1059 |
| B | HOH1070 |
| B | HOH1185 |
| site_id | BC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PLP C 401 |
| Chain | Residue |
| C | VAL94 |
| C | VAL95 |
| C | PRO96 |
| C | TYR119 |
| C | CYS167 |
| C | ASN171 |
| C | ASP199 |
| C | ILE201 |
| C | HIS202 |
| C | HOH852 |
| C | HOH900 |
| C | HOH1139 |
| C | HOH1171 |
| D | TYR60 |
| site_id | BC3 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE PLS C 501 |
| Chain | Residue |
| C | ILE34 |
| C | ALA35 |
| C | GLY93 |
| C | VAL94 |
| C | VAL95 |
| C | TYR119 |
| C | CYS167 |
| C | ASN171 |
| C | ASP199 |
| C | ILE201 |
| C | HIS202 |
| C | ARG365 |
| C | HOH852 |
| C | HOH900 |
| C | HOH911 |
| C | HOH933 |
| C | HOH1139 |
| C | HOH1171 |
| D | TYR60 |
| D | EPE601 |
| site_id | BC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE EPE C 601 |
| Chain | Residue |
| C | TYR60 |
| C | GLU268 |
| C | HOH877 |
| D | TYR18 |
| D | TRP33 |
| D | VAL95 |
| D | TYR119 |
| D | PLS501 |
| D | EPE602 |
| D | HOH1037 |
| D | HOH1144 |
| site_id | BC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EPE C 602 |
| Chain | Residue |
| A | EPE601 |
| B | PRO120 |
| B | PRO121 |
| B | HOH849 |
| B | HOH927 |
| B | HOH1100 |
| B | HOH1201 |
| C | HOH1040 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EPE C 603 |
| Chain | Residue |
| C | PRO120 |
| C | PRO121 |
| C | HOH911 |
| C | HOH1068 |
| C | HOH1097 |
| C | HOH1129 |
| D | EPE601 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA C 701 |
| Chain | Residue |
| C | SER358 |
| C | HOH923 |
| C | HOH949 |
| C | HOH1058 |
| C | HOH1114 |
| site_id | BC8 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE PLS D 501 |
| Chain | Residue |
| C | TYR60 |
| C | EPE601 |
| D | ILE34 |
| D | ALA35 |
| D | GLY93 |
| D | VAL94 |
| D | VAL95 |
| D | TYR119 |
| D | CYS167 |
| D | ASN171 |
| D | ASP199 |
| D | ILE201 |
| D | HIS202 |
| D | LYS234 |
| D | ARG365 |
| D | HOH828 |
| D | HOH851 |
| D | HOH907 |
| D | HOH1037 |
| D | HOH1144 |
| site_id | BC9 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE EPE D 601 |
| Chain | Residue |
| C | TYR18 |
| C | TRP33 |
| C | VAL95 |
| C | TYR119 |
| C | PLS501 |
| C | EPE603 |
| C | HOH1097 |
| C | HOH1129 |
| C | HOH1139 |
| D | TYR60 |
| D | GLU268 |
| D | HOH927 |
| site_id | CC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE EPE D 602 |
| Chain | Residue |
| A | ASP336 |
| A | PHE339 |
| C | EPE601 |
| D | PRO120 |
| D | PRO121 |
| D | ASP355 |
| D | HOH989 |
| D | HOH1039 |
| D | HOH1063 |
| D | HOH1067 |
| D | HOH1106 |
| D | HOH1144 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EPE D 603 |
| Chain | Residue |
| D | ASP84 |
| D | LYS85 |
| D | GLU86 |
| D | HOH965 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA D 701 |
| Chain | Residue |
| D | SER358 |
| D | HOH827 |
| D | HOH939 |
| D | HOH964 |
| D | HOH966 |
| D | HOH1017 |
