3B1C
Crystal structure of betaC-S lyase from Streptococcus anginosus: Internal aldimine form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0047804 | molecular_function | cysteine-S-conjugate beta-lyase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0047804 | molecular_function | cysteine-S-conjugate beta-lyase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0047804 | molecular_function | cysteine-S-conjugate beta-lyase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0047804 | molecular_function | cysteine-S-conjugate beta-lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PLP A 401 |
| Chain | Residue |
| A | GLY93 |
| A | LYS234 |
| A | HOH762 |
| A | HOH825 |
| A | HOH860 |
| B | TYR60 |
| A | VAL94 |
| A | VAL95 |
| A | TYR119 |
| A | CYS167 |
| A | ASN171 |
| A | ASP199 |
| A | ILE201 |
| A | HIS202 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 501 |
| Chain | Residue |
| A | ILE34 |
| A | ALA35 |
| A | TYR119 |
| A | ASN351 |
| A | ARG365 |
| A | HOH762 |
| A | HOH785 |
| A | HOH884 |
| A | HOH1036 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 601 |
| Chain | Residue |
| A | THR334 |
| A | ASP335 |
| A | GLU361 |
| A | HOH795 |
| D | SO4502 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 602 |
| Chain | Residue |
| A | GLU78 |
| A | LYS285 |
| A | LYS292 |
| A | HOH1013 |
| A | HOH1032 |
| B | ASP221 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 603 |
| Chain | Residue |
| A | ILE88 |
| A | VAL89 |
| A | PHE90 |
| A | HOH987 |
| A | HOH1027 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 604 |
| Chain | Residue |
| A | HIS259 |
| A | HOH870 |
| C | ALA337 |
| C | THR340 |
| C | HOH883 |
| C | HOH990 |
| site_id | AC7 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PLP B 401 |
| Chain | Residue |
| A | TYR60 |
| A | HOH942 |
| B | GLY93 |
| B | VAL94 |
| B | VAL95 |
| B | TYR119 |
| B | CYS167 |
| B | ASN171 |
| B | ASP199 |
| B | ILE201 |
| B | HIS202 |
| B | LYS234 |
| B | HOH723 |
| B | HOH815 |
| B | HOH843 |
| B | HOH1080 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 501 |
| Chain | Residue |
| B | ILE34 |
| B | ALA35 |
| B | TYR119 |
| B | ASN351 |
| B | ARG365 |
| B | HOH780 |
| B | HOH843 |
| B | HOH1019 |
| B | HOH1080 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 502 |
| Chain | Residue |
| B | ARG127 |
| B | LEU133 |
| B | HOH701 |
| B | HOH901 |
| B | HOH915 |
| B | HOH947 |
| B | HOH989 |
| C | GOL601 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 601 |
| Chain | Residue |
| B | THR334 |
| B | ASP335 |
| B | GLU361 |
| B | HOH954 |
| C | ARG127 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 602 |
| Chain | Residue |
| B | GLU78 |
| B | LYS285 |
| B | LYS292 |
| B | HOH1036 |
| site_id | BC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 603 |
| Chain | Residue |
| B | ALA337 |
| B | THR340 |
| B | LEU341 |
| B | GLN345 |
| B | HOH855 |
| B | HOH861 |
| B | HOH912 |
| B | HOH1071 |
| D | HIS259 |
| site_id | BC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PLP C 401 |
| Chain | Residue |
| C | TYR119 |
| C | CYS167 |
| C | ASN171 |
| C | ASP199 |
| C | ILE201 |
| C | HIS202 |
| C | LYS234 |
| C | HOH745 |
| C | HOH769 |
| C | HOH778 |
| C | HOH869 |
| D | TYR60 |
| C | GLY93 |
| C | VAL94 |
| C | VAL95 |
| site_id | BC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 C 501 |
| Chain | Residue |
| C | ILE34 |
| C | ALA35 |
| C | TYR119 |
| C | ASN351 |
| C | ARG365 |
| C | HOH745 |
| C | HOH819 |
| C | HOH869 |
| C | HOH1053 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 601 |
| Chain | Residue |
| B | ARG127 |
| B | SO4502 |
| B | HOH947 |
| C | THR334 |
| C | ASP335 |
| C | GLU361 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 602 |
| Chain | Residue |
| C | GLU78 |
| C | LYS285 |
| C | LEU288 |
| C | LYS292 |
| C | HOH861 |
| C | HOH1043 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 603 |
| Chain | Residue |
| A | THR340 |
| A | LEU341 |
| A | HOH791 |
| A | HOH924 |
| C | HIS259 |
| C | HOH1020 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 604 |
| Chain | Residue |
| C | GLN28 |
| C | GLN345 |
| C | ALA346 |
| C | HOH1025 |
| site_id | CC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PLP D 401 |
| Chain | Residue |
| C | TYR60 |
| C | HOH974 |
| D | GLY93 |
| D | VAL94 |
| D | VAL95 |
| D | TYR119 |
| D | CYS167 |
| D | ASN171 |
| D | ASP199 |
| D | ILE201 |
| D | HIS202 |
| D | LYS234 |
| D | HOH720 |
| D | HOH804 |
| D | HOH906 |
| site_id | CC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 D 501 |
| Chain | Residue |
| D | ILE34 |
| D | ALA35 |
| D | TYR119 |
| D | ASN351 |
| D | ARG365 |
| D | HOH804 |
| D | HOH874 |
| D | HOH981 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 502 |
| Chain | Residue |
| A | GOL601 |
| D | ARG127 |
| D | HOH733 |
| D | HOH858 |
| D | HOH984 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL D 601 |
| Chain | Residue |
| A | ARG127 |
| D | THR334 |
| D | ASP335 |
| D | GLU361 |
| site_id | CC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL D 602 |
| Chain | Residue |
| D | ASP73 |
| D | TRP74 |
| D | SER77 |
| D | GLU78 |
| D | LYS191 |
| D | TYR281 |
| D | LYS285 |
| D | HOH746 |
| D | HOH761 |
| D | HOH969 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 603 |
| Chain | Residue |
| D | ILE88 |
| D | VAL89 |
| D | PHE90 |
| D | HOH713 |
| D | HOH1018 |
