3B0Y
K263D mutant of PolX from Thermus thermophilus HB8 complexed with Ca-dGTP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0006260 | biological_process | DNA replication |
| A | 0006281 | biological_process | DNA repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0042578 | molecular_function | phosphoric ester hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071897 | biological_process | DNA biosynthetic process |
| A | 0140078 | molecular_function | class I DNA-(apurinic or apyrimidinic site) endonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE DGT A 576 |
| Chain | Residue |
| A | ARG157 |
| A | LEU259 |
| A | THR260 |
| A | GLY261 |
| A | ASP263 |
| A | CA578 |
| A | CA579 |
| A | HOH597 |
| A | HOH638 |
| A | HOH689 |
| A | HOH805 |
| A | GLY187 |
| A | HOH809 |
| A | HOH876 |
| A | HOH888 |
| A | HOH907 |
| A | SER188 |
| A | ARG191 |
| A | VAL196 |
| A | GLY197 |
| A | ASP198 |
| A | ASP200 |
| A | TYR258 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 577 |
| Chain | Residue |
| A | GLU413 |
| A | HIS440 |
| A | HIS468 |
| A | ARG506 |
| A | HOH615 |
| A | HOH894 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 578 |
| Chain | Residue |
| A | ASP198 |
| A | ASP200 |
| A | DGT576 |
| A | HOH638 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 579 |
| Chain | Residue |
| A | ASP198 |
| A | ASP200 |
| A | ASP243 |
| A | DGT576 |
| A | HOH661 |
| A | HOH689 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 580 |
| Chain | Residue |
| A | ARG175 |
| A | LEU177 |
| A | VAL180 |
| A | HOH781 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA A 581 |
| Chain | Residue |
| A | MET56 |
| A | LEU58 |
| A | VAL61 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 582 |
| Chain | Residue |
| A | ARG182 |
| A | THR296 |
| A | GLU297 |
