3B0X
K263A mutant of PolX from Thermus thermophilus HB8 complexed with Ca-dGTP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0006281 | biological_process | DNA repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0042578 | molecular_function | phosphoric ester hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071897 | biological_process | DNA biosynthetic process |
| A | 0140078 | molecular_function | class I DNA-(apurinic or apyrimidinic site) endonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 576 |
| Chain | Residue |
| A | ASP349 |
| A | HIS374 |
| A | HIS531 |
| A | HOH872 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 577 |
| Chain | Residue |
| A | GLU413 |
| A | HIS440 |
| A | HIS468 |
| A | HOH639 |
| A | HOH1051 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 578 |
| Chain | Residue |
| A | ASP198 |
| A | ASP200 |
| A | DGT583 |
| A | HOH675 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 579 |
| Chain | Residue |
| A | ASP198 |
| A | ASP200 |
| A | ASP243 |
| A | DGT583 |
| A | HOH704 |
| A | HOH726 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 580 |
| Chain | Residue |
| A | ARG175 |
| A | LEU177 |
| A | VAL180 |
| A | HOH791 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA A 581 |
| Chain | Residue |
| A | MET56 |
| A | LEU58 |
| A | VAL61 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 582 |
| Chain | Residue |
| A | ARG182 |
| A | THR296 |
| A | GLU297 |
| site_id | AC8 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE DGT A 583 |
| Chain | Residue |
| A | ARG157 |
| A | GLY187 |
| A | SER188 |
| A | ARG191 |
| A | VAL196 |
| A | GLY197 |
| A | ASP198 |
| A | ASP200 |
| A | TYR258 |
| A | LEU259 |
| A | THR260 |
| A | GLY261 |
| A | ARG270 |
| A | CA578 |
| A | CA579 |
| A | HOH617 |
| A | HOH641 |
| A | HOH675 |
| A | HOH726 |
| A | HOH773 |
| A | HOH965 |
| A | HOH1032 |
| A | HOH1079 |
| A | HOH1120 |
| A | HOH1134 |
