3B0X

K263A mutant of PolX from Thermus thermophilus HB8 complexed with Ca-dGTP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003824	molecular_function	catalytic activity
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006259	biological_process	DNA metabolic process
A	0006281	biological_process	DNA repair
A	0008270	molecular_function	zinc ion binding
A	0042578	molecular_function	phosphoric ester hydrolase activity
A	0071897	biological_process	DNA biosynthetic process
A	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 576

Chain	Residue
A	ASP349
A	HIS374
A	HIS531
A	HOH872

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 577

Chain	Residue
A	GLU413
A	HIS440
A	HIS468
A	HOH639
A	HOH1051

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 578

Chain	Residue
A	ASP198
A	ASP200
A	DGT583
A	HOH675

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 579

Chain	Residue
A	ASP198
A	ASP200
A	ASP243
A	DGT583
A	HOH704
A	HOH726

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 580

Chain	Residue
A	ARG175
A	LEU177
A	VAL180
A	HOH791

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site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA A 581

Chain	Residue
A	MET56
A	LEU58
A	VAL61

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site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 582

Chain	Residue
A	ARG182
A	THR296
A	GLU297

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site_id	AC8
Number of Residues	25
Details	BINDING SITE FOR RESIDUE DGT A 583

Chain	Residue
A	ARG157
A	GLY187
A	SER188
A	ARG191
A	VAL196
A	GLY197
A	ASP198
A	ASP200
A	TYR258
A	LEU259
A	THR260
A	GLY261
A	ARG270
A	CA578
A	CA579
A	HOH617
A	HOH641
A	HOH675
A	HOH726
A	HOH773
A	HOH965
A	HOH1032
A	HOH1079
A	HOH1120
A	HOH1134

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