3B0O
Crystal structure of alpha-lactalbumin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000139 | cellular_component | Golgi membrane |
| A | 0003796 | molecular_function | lysozyme activity |
| A | 0004461 | molecular_function | lactose synthase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005796 | cellular_component | Golgi lumen |
| A | 0005989 | biological_process | lactose biosynthetic process |
| A | 0006915 | biological_process | apoptotic process |
| A | 0007165 | biological_process | signal transduction |
| A | 0007267 | biological_process | cell-cell signaling |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050829 | biological_process | defense response to Gram-negative bacterium |
| A | 0050830 | biological_process | defense response to Gram-positive bacterium |
| B | 0000139 | cellular_component | Golgi membrane |
| B | 0003796 | molecular_function | lysozyme activity |
| B | 0004461 | molecular_function | lactose synthase activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0005796 | cellular_component | Golgi lumen |
| B | 0005989 | biological_process | lactose biosynthetic process |
| B | 0006915 | biological_process | apoptotic process |
| B | 0007165 | biological_process | signal transduction |
| B | 0007267 | biological_process | cell-cell signaling |
| B | 0032991 | cellular_component | protein-containing complex |
| B | 0042742 | biological_process | defense response to bacterium |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050829 | biological_process | defense response to Gram-negative bacterium |
| B | 0050830 | biological_process | defense response to Gram-positive bacterium |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 124 |
| Chain | Residue |
| A | LYS79 |
| A | ASP82 |
| A | ASP84 |
| A | ASP87 |
| A | ASP88 |
| A | HOH128 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA B 124 |
| Chain | Residue |
| B | ASP87 |
| B | ASP88 |
| B | HOH132 |
| B | HOH133 |
| B | LYS79 |
| B | ASP82 |
| B | ASP84 |
Functional Information from PROSITE/UniProt
| site_id | PS00128 |
| Number of Residues | 19 |
| Details | GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CdisCdkFlddDItddimC |
| Chain | Residue | Details |
| A | CYS73-CYS91 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:9537992, ECO:0007744|PDB:1A4V |
| Chain | Residue | Details |
| A | THR38 | |
| A | GLN39 | |
| A | LEU81 | |
| A | ASP83 | |
| B | THR38 | |
| B | GLN39 | |
| B | LEU81 | |
| B | ASP83 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:8366079, ECO:0007744|PDB:1HML |
| Chain | Residue | Details |
| A | GLU49 | |
| A | GLU116 | |
| B | GLU49 | |
| B | GLU116 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:8366079, ECO:0000269|PubMed:9537992, ECO:0007744|PDB:1A4V, ECO:0007744|PDB:1HML |
| Chain | Residue | Details |
| A | LYS79 | |
| B | ASP88 | |
| A | ASP82 | |
| A | ASP84 | |
| A | ASP87 | |
| A | ASP88 | |
| B | LYS79 | |
| B | ASP82 | |
| B | ASP84 | |
| B | ASP87 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18780401 |
| Chain | Residue | Details |
| A | ASN45 | |
| B | ASN45 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; atypical; partial => ECO:0000269|Ref.9 |
| Chain | Residue | Details |
| A | ASN71 | |
| B | ASN71 |
