3AZA
Beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Plasmodium falciparum in complex with NAS91-10
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016836 | molecular_function | hydro-lyase activity |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016836 | molecular_function | hydro-lyase activity |
| C | 0006633 | biological_process | fatty acid biosynthetic process |
| C | 0016836 | molecular_function | hydro-lyase activity |
| D | 0006633 | biological_process | fatty acid biosynthetic process |
| D | 0016836 | molecular_function | hydro-lyase activity |
| E | 0006633 | biological_process | fatty acid biosynthetic process |
| E | 0016836 | molecular_function | hydro-lyase activity |
| F | 0006633 | biological_process | fatty acid biosynthetic process |
| F | 0016836 | molecular_function | hydro-lyase activity |
| G | 0006633 | biological_process | fatty acid biosynthetic process |
| G | 0016836 | molecular_function | hydro-lyase activity |
| H | 0006633 | biological_process | fatty acid biosynthetic process |
| H | 0016836 | molecular_function | hydro-lyase activity |
| I | 0006633 | biological_process | fatty acid biosynthetic process |
| I | 0016836 | molecular_function | hydro-lyase activity |
| J | 0006633 | biological_process | fatty acid biosynthetic process |
| J | 0016836 | molecular_function | hydro-lyase activity |
| K | 0006633 | biological_process | fatty acid biosynthetic process |
| K | 0016836 | molecular_function | hydro-lyase activity |
| L | 0006633 | biological_process | fatty acid biosynthetic process |
| L | 0016836 | molecular_function | hydro-lyase activity |
| M | 0006633 | biological_process | fatty acid biosynthetic process |
| M | 0016836 | molecular_function | hydro-lyase activity |
| N | 0006633 | biological_process | fatty acid biosynthetic process |
| N | 0016836 | molecular_function | hydro-lyase activity |
| O | 0006633 | biological_process | fatty acid biosynthetic process |
| O | 0016836 | molecular_function | hydro-lyase activity |
| P | 0006633 | biological_process | fatty acid biosynthetic process |
| P | 0016836 | molecular_function | hydro-lyase activity |
| Q | 0006633 | biological_process | fatty acid biosynthetic process |
| Q | 0016836 | molecular_function | hydro-lyase activity |
| R | 0006633 | biological_process | fatty acid biosynthetic process |
| R | 0016836 | molecular_function | hydro-lyase activity |
| S | 0006633 | biological_process | fatty acid biosynthetic process |
| S | 0016836 | molecular_function | hydro-lyase activity |
| T | 0006633 | biological_process | fatty acid biosynthetic process |
| T | 0016836 | molecular_function | hydro-lyase activity |
| U | 0006633 | biological_process | fatty acid biosynthetic process |
| U | 0016836 | molecular_function | hydro-lyase activity |
| V | 0006633 | biological_process | fatty acid biosynthetic process |
| V | 0016836 | molecular_function | hydro-lyase activity |
| W | 0006633 | biological_process | fatty acid biosynthetic process |
| W | 0016836 | molecular_function | hydro-lyase activity |
| X | 0006633 | biological_process | fatty acid biosynthetic process |
| X | 0016836 | molecular_function | hydro-lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 2 |
| Chain | Residue |
| A | PRO101 |
| A | PHE102 |
| B | PHE129 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE KM0 B 2 |
| Chain | Residue |
| B | GLN151 |
| B | PHE169 |
| B | LEU170 |
| B | PHE171 |
| B | PHE226 |
| A | HIS133 |
| A | PHE134 |
| A | GLY142 |
| B | HIS98 |
| B | GLU147 |
| B | ALA150 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 1 |
| Chain | Residue |
| C | PRO101 |
| C | PHE129 |
| D | PRO101 |
| D | PHE129 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE KM0 C 3 |
| Chain | Residue |
| C | HIS98 |
| C | GLU147 |
| C | ALA150 |
| C | GLN151 |
| C | GLY154 |
| C | PHE169 |
| C | LEU170 |
| C | PHE171 |
| C | PHE226 |
| D | HIS133 |
| D | PHE134 |
| D | GLY142 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE KM0 D 1 |
| Chain | Residue |
| C | HIS133 |
| C | PHE134 |
| C | GLY142 |
| D | HIS98 |
| D | GLU147 |
| D | ALA150 |
| D | GLN151 |
| D | GLY154 |
| D | PHE169 |
| D | LEU170 |
| D | PHE171 |
| D | PHE226 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL E 3 |
| Chain | Residue |
| E | PRO101 |
| E | PRO128 |
| F | PRO128 |
| F | PHE129 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL G 4 |
| Chain | Residue |
| G | PRO101 |
| G | PHE129 |
| H | PRO101 |
| H | PHE102 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL J 5 |
| Chain | Residue |
| I | PRO101 |
| I | PRO128 |
| J | PRO101 |
| J | PHE129 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE KM0 M 4 |
| Chain | Residue |
| M | HIS98 |
| M | GLU147 |
| M | ALA150 |
| M | GLN151 |
| M | GLY154 |
| M | PHE169 |
| M | LEU170 |
| M | PHE171 |
| M | PHE226 |
| N | HIS133 |
| N | PHE134 |
| N | GLY142 |
| site_id | BC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL N 6 |
| Chain | Residue |
| N | PRO101 |
| site_id | BC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE KM0 O 5 |
| Chain | Residue |
| O | HIS98 |
| O | GLU147 |
| O | ALA150 |
| O | PHE169 |
| O | LEU170 |
| O | PHE171 |
| O | PHE226 |
| P | HIS133 |
| P | PHE134 |
| P | MET140 |
| P | PRO141 |
| P | GLY142 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL P 7 |
| Chain | Residue |
| O | PRO101 |
| P | PRO101 |
| P | PRO128 |
| site_id | BC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE KM0 P 6 |
| Chain | Residue |
| O | HIS133 |
| O | PHE134 |
| O | GLY142 |
| P | HIS98 |
| P | GLU147 |
| P | ALA150 |
| P | GLN151 |
| P | PHE169 |
| P | LEU170 |
| P | PHE171 |
| P | PHE226 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL Q 8 |
| Chain | Residue |
| Q | PRO101 |
| Q | PRO128 |
| Q | PHE129 |
| R | PRO101 |
| site_id | BC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE KM0 Q 7 |
| Chain | Residue |
| Q | ALA150 |
| Q | GLN151 |
| Q | PHE169 |
| Q | LEU170 |
| Q | PHE171 |
| Q | PHE226 |
| R | HIS133 |
| R | PHE134 |
| R | GLY142 |
| Q | HIS98 |
| Q | GLU147 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL T 9 |
| Chain | Residue |
| S | PRO101 |
| S | PRO128 |
| S | PHE129 |
| T | PRO101 |
| T | PRO128 |
| site_id | BC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE KM0 U 8 |
| Chain | Residue |
| U | HIS98 |
| U | GLU147 |
| U | ALA150 |
| U | GLN151 |
| U | GLY154 |
| U | PHE169 |
| U | LEU170 |
| U | PHE171 |
| U | PHE226 |
| V | HIS133 |
| V | PHE134 |
| V | GLY142 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL V 10 |
| Chain | Residue |
| U | PHE102 |
| U | PRO128 |
| V | PRO101 |
| V | PHE102 |
| V | PHE129 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL W 11 |
| Chain | Residue |
| W | PRO101 |
| W | PHE129 |
| X | PRO101 |
| X | PHE102 |
| X | PHE129 |
