3AXS
Complex structure of tRNA methyltransferase Trm1 from Aquifex aeolicus with sinefungin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0008033 | biological_process | tRNA processing |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016423 | molecular_function | tRNA (guanine) methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030488 | biological_process | tRNA methylation |
| A | 0032259 | biological_process | methylation |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0160103 | molecular_function | tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity |
| A | 0160104 | molecular_function | tRNA (guanine(26)-N2)-dimethyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | CYS247 |
| A | CYS250 |
| A | CYS266 |
| A | CYS269 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE SFG A 501 |
| Chain | Residue |
| A | ARG66 |
| A | ASP84 |
| A | ILE85 |
| A | MET112 |
| A | GLU113 |
| A | ALA114 |
| A | ASP132 |
| A | PHE134 |
| A | HOH395 |
| A | HOH399 |
| A | HOH487 |
| A | ARG36 |
| A | LEU60 |
| A | SER61 |
| A | ALA62 |
| A | ILE65 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 502 |
| Chain | Residue |
| A | SER21 |
| A | SER22 |
| A | ARG31 |
| A | LEU218 |
| A | HIS219 |
| A | ARG344 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 503 |
| Chain | Residue |
| A | ALA162 |
| A | TYR168 |
| A | HIS219 |
| A | ARG344 |
| A | HOH436 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 504 |
| Chain | Residue |
| A | TYR168 |
| A | PRO169 |
| A | LYS170 |
| A | THR171 |
| A | HOH410 |
| A | HOH481 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 506 |
| Chain | Residue |
| A | HIS110 |
| A | GLY111 |
| A | MET112 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 393 |
| Chain | Residue |
| A | ARG182 |
| A | LYS186 |
| A | LYS305 |
| A | ARG309 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 373 |
| Details | Domain: {"description":"Trm1 methyltransferase","evidences":[{"source":"HAMAP-Rule","id":"MF_00290","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21844194","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3AXT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21844194","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3AXS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AXT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
