3AX6

Crystal structure of N5-carboxyaminoimidazole ribonucleotide synthetase from Thermotoga maritima

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004638	molecular_function	phosphoribosylaminoimidazole carboxylase activity
A	0005524	molecular_function	ATP binding
A	0006164	biological_process	purine nucleotide biosynthetic process
A	0006189	biological_process	'de novo' IMP biosynthetic process
A	0016874	molecular_function	ligase activity
A	0034028	molecular_function	5-(carboxyamino)imidazole ribonucleotide synthase activity
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0004638	molecular_function	phosphoribosylaminoimidazole carboxylase activity
B	0005524	molecular_function	ATP binding
B	0006164	biological_process	purine nucleotide biosynthetic process
B	0006189	biological_process	'de novo' IMP biosynthetic process
B	0016874	molecular_function	ligase activity
B	0034028	molecular_function	5-(carboxyamino)imidazole ribonucleotide synthase activity
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0004638	molecular_function	phosphoribosylaminoimidazole carboxylase activity
C	0005524	molecular_function	ATP binding
C	0006164	biological_process	purine nucleotide biosynthetic process
C	0006189	biological_process	'de novo' IMP biosynthetic process
C	0016874	molecular_function	ligase activity
C	0034028	molecular_function	5-(carboxyamino)imidazole ribonucleotide synthase activity
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0004638	molecular_function	phosphoribosylaminoimidazole carboxylase activity
D	0005524	molecular_function	ATP binding
D	0006164	biological_process	purine nucleotide biosynthetic process
D	0006189	biological_process	'de novo' IMP biosynthetic process
D	0016874	molecular_function	ligase activity
D	0034028	molecular_function	5-(carboxyamino)imidazole ribonucleotide synthase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ADP A 381

Chain	Residue
A	LYS101
A	HOH521
A	LYS138
A	GLU169
A	GLU170
A	PHE171
A	VAL172
A	GLU177
A	PHE246
A	ASN256

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site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE ADP B 381

Chain	Residue
B	LYS101
B	VAL136
B	LYS138
B	VAL149
B	GLU169
B	GLU170
B	PHE171
B	VAL172
B	GLU177
B	GLU244
B	PHE246
B	ASN256

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site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ADP C 381

Chain	Residue
C	LYS101
C	LYS138
C	GLU169
C	GLU170
C	PHE171
C	VAL172
C	GLU177
C	PHE246
C	ASN256
C	HOH385

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site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE ADP D 381

Chain	Residue
D	LYS138
D	VAL149
D	GLU169
D	GLU170
D	PHE171
D	VAL172
D	GLU177
D	ASN256
D	HOH570

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