Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005507 | molecular_function | copper ion binding |
| B | 0042438 | biological_process | melanin biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CU A 500 |
| Chain | Residue |
| A | HIS38 |
| A | HIS54 |
| A | HIS63 |
| A | CU501 |
| A | HOH509 |
| B | TYR98 |
| B | HOH537 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CU A 501 |
| Chain | Residue |
| A | HIS216 |
| A | CU500 |
| A | HOH509 |
| B | HOH537 |
| A | HIS190 |
| A | HIS194 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CU A 503 |
| Chain | Residue |
| A | HIS277 |
| A | HIS277 |
| A | HIS279 |
| A | HIS279 |
| A | HOH663 |
| A | HOH663 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CU A 504 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 A 505 |
| Chain | Residue |
| A | TYR165 |
| A | TRP223 |
| A | TRP226 |
| A | GLN227 |
| A | ALA234 |
| A | TYR235 |
| A | LEU263 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NO3 A 507 |
| Chain | Residue |
| A | THR238 |
| A | ASP246 |
| A | LEU247 |
| A | ASN248 |
| B | LYS50 |
| B | HOH602 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NO3 A 508 |
| Chain | Residue |
| A | ARG228 |
| A | HIS265 |
| A | THR270 |
| A | PHE271 |
| A | LEU274 |
| A | HOH733 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CU B 502 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE NO3 B 506 |
| Chain | Residue |
| A | GLY125 |
| A | PRO128 |
| A | HOH674 |
| B | THR103 |
| B | ARG105 |
| B | ALA106 |
| B | ARG109 |
| B | HOH628 |
| B | HOH652 |
Functional Information from PROSITE/UniProt
| site_id | PS00497 |
| Number of Residues | 18 |
| Details | TYROSINASE_1 Tyrosinase CuA-binding region signature. Hrsps.FLpWHRrfLldfE |
| Chain | Residue | Details |
| A | HIS54-GLU71 | |
| site_id | PS00498 |
| Number of Residues | 12 |
| Details | TYROSINASE_2 Tyrosinase and hemocyanins CuB-binding region signature. DPvFWlhHayvD |
| Chain | Residue | Details |
| A | ASP209-ASP220 | |
