Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005507 | molecular_function | copper ion binding |
| B | 0042438 | biological_process | melanin biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CU A 500 |
| Chain | Residue |
| A | HIS190 |
| A | HIS194 |
| A | HIS216 |
| B | HOH617 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CU A 502 |
| Chain | Residue |
| A | HOH836 |
| A | HOH836 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NO3 A 504 |
| Chain | Residue |
| A | GLN227 |
| A | ALA234 |
| A | TYR235 |
| A | LEU263 |
| A | HOH743 |
| A | TYR165 |
| A | TRP223 |
| A | TRP226 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NO3 A 506 |
| Chain | Residue |
| A | THR238 |
| A | GLY239 |
| A | ASP246 |
| A | LEU247 |
| A | ASN248 |
| A | HOH730 |
| B | LYS50 |
| B | HOH576 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 A 507 |
| Chain | Residue |
| A | ARG228 |
| A | HIS265 |
| A | THR266 |
| A | THR270 |
| A | PHE271 |
| A | LEU274 |
| A | HOH697 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CU B 501 |
| Chain | Residue |
| B | GLU67 |
| B | HIS68 |
| B | HIS82 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 B 503 |
| Chain | Residue |
| B | HIS82 |
| B | VAL83 |
| B | MET84 |
| B | ILE92 |
| B | SER93 |
| B | VAL94 |
| B | HIS97 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 B 505 |
| Chain | Residue |
| A | GLY125 |
| A | PRO128 |
| B | THR103 |
| B | ARG105 |
| B | ALA106 |
| B | ARG109 |
| B | HOH670 |
Functional Information from PROSITE/UniProt
| site_id | PS00497 |
| Number of Residues | 18 |
| Details | TYROSINASE_1 Tyrosinase CuA-binding region signature. Hrsps.FLpWHRrfLldfE |
| Chain | Residue | Details |
| A | HIS54-GLU71 | |
| site_id | PS00498 |
| Number of Residues | 12 |
| Details | TYROSINASE_2 Tyrosinase and hemocyanins CuB-binding region signature. DPvFWlhHayvD |
| Chain | Residue | Details |
| A | ASP209-ASP220 | |
