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3AWJ

Crystal structure of the Huperzia serrata polyketide synthase 1 complexed with CoA-SH

Functional Information from GO Data
ChainGOidnamespacecontents
A0009058biological_processbiosynthetic process
A0016740molecular_functiontransferase activity
A0016746molecular_functionacyltransferase activity
A0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
A0030639biological_processpolyketide biosynthetic process
B0009058biological_processbiosynthetic process
B0016740molecular_functiontransferase activity
B0016746molecular_functionacyltransferase activity
B0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
B0030639biological_processpolyketide biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues15
DetailsBINDING SITE FOR RESIDUE COA A 500
ChainResidue
AARG68
ALYS279
AVAL281
AGLY315
AGLY316
APRO317
AALA318
AILE69
ALYS72
ACSD174
AASP217
AVAL220
ALEU224
ALEU277
ALEU278

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 501
ChainResidue
APRO37
ATHR38
AASN39
AHIS81

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B 502
ChainResidue
BPRO37
BTHR38
BASN39
BHIS81

Functional Information from PROSITE/UniProt
site_idPS00441
Number of Residues17
DetailsCHALCONE_SYNTH Chalcone and stilbene synthases active site. RVmLyQqGCYAGATvLR
ChainResidueDetails
AARG166-ARG182

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PDB entries from 2025-07-02

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