3AW8
Crystal structure of N5-carboxyaminoimidazole ribonucleotide synthetase from Thermus thermophilus HB8
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004638 | molecular_function | phosphoribosylaminoimidazole carboxylase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0034028 | molecular_function | 5-(carboxyamino)imidazole ribonucleotide synthase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004638 | molecular_function | phosphoribosylaminoimidazole carboxylase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| B | 0034028 | molecular_function | 5-(carboxyamino)imidazole ribonucleotide synthase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE AMP A 370 |
| Chain | Residue |
| A | ARG97 |
| A | GLU258 |
| A | HOH429 |
| A | LEU135 |
| A | LYS137 |
| A | GLN148 |
| A | GLU172 |
| A | VAL175 |
| A | GLU180 |
| A | HIS203 |
| A | PHE248 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 371 |
| Chain | Residue |
| A | CYS35 |
| A | LYS328 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE AMP B 370 |
| Chain | Residue |
| B | ARG97 |
| B | LEU135 |
| B | LYS137 |
| B | GLN148 |
| B | GLU172 |
| B | PHE174 |
| B | VAL175 |
| B | PHE177 |
| B | GLU180 |
| B | HIS203 |
| B | PHE248 |
| B | GLU258 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 371 |
| Chain | Residue |
| B | CYS35 |
| B | LYS328 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 372 |
| Chain | Residue |
| B | ALA17 |
| B | SER277 |
| B | HOH445 |
