Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 336 |
| Chain | Residue |
| A | ASN118 |
| A | THR119 |
| A | ASP120 |
| A | PHE121 |
| A | PRO159 |
| A | VAL162 |
| A | MET163 |
| A | ILE164 |
| A | HOH358 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 337 |
| Chain | Residue |
| A | VAL66 |
| A | PHE113 |
| A | HOH446 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 338 |
| Chain | Residue |
| A | ARG80 |
| A | ARG155 |
| A | LEU178 |
| A | MET334 |
| A | GLY335 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 339 |
| Chain | Residue |
| A | PHE232 |
| A | PHE284 |
| A | HOH455 |
| A | HOH467 |
| A | HOH648 |
| A | HOH712 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 340 |
| Chain | Residue |
| A | VAL11 |
| A | HIS148 |
| A | TYR211 |
| A | SER212 |
| A | MET215 |
| A | ALA315 |
| A | HOH431 |
| A | HOH452 |
| A | HOH457 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 341 |
| Chain | Residue |
| A | PHE197 |
| A | GLU230 |
| A | HOH436 |
| A | HOH547 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 342 |
| Chain | Residue |
| A | ASN117 |
| A | THR119 |
| A | ILE164 |
| A | ASP165 |
| A | HIS166 |
| A | GLU167 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 343 |
| Chain | Residue |
| A | THR127 |
| A | ASP132 |
| A | HIS166 |
| A | ARG169 |
| A | HOH612 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 344 |
| Chain | Residue |
| A | GLN36 |
| A | TYR39 |
| A | ILE69 |
| A | VAL101 |
| A | ASP103 |
| A | EDO346 |
| A | HOH397 |
| A | HOH469 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 345 |
| Chain | Residue |
| A | GLN36 |
| A | ASP37 |
| A | TYR39 |
| A | ILE59 |
| A | HOH397 |
| A | HOH527 |
| A | HOH656 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 346 |
| Chain | Residue |
| A | LEU41 |
| A | ASP103 |
| A | PRO104 |
| A | VAL105 |
| A | EDO344 |
| A | HOH347 |
| A | HOH469 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGKYSEVFeAinitnnek..........VVVK |
| Chain | Residue | Details |
| A | LEU45-LYS68 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ImHrDVKphNVMI |
| Chain | Residue | Details |
| A | ILE152-ILE164 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 285 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Region: {"description":"Interaction with beta subunit","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
