3ASV

The Closed form of serine dehydrogenase complexed with NADP+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
B	0016491	molecular_function	oxidoreductase activity
C	0016491	molecular_function	oxidoreductase activity
D	0016491	molecular_function	oxidoreductase activity
E	0016491	molecular_function	oxidoreductase activity
F	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	34
Details	BINDING SITE FOR RESIDUE NAP A 301

Chain	Residue
A	GLY7
A	ASP54
A	VAL55
A	ARG56
A	ASN81
A	ALA82
A	GLY83
A	ILE132
A	GLY133
A	SER134
A	TYR147
A	THR9
A	LYS151
A	PRO177
A	GLY178
A	VAL180
A	THR183
A	GLU184
A	PHE185
A	PO4311
A	HOH1011
A	HOH1097
A	ALA10
A	HOH1186
A	HOH1243
A	HOH1254
A	HOH1278
A	HOH1315
A	GLY11
A	PHE12
A	GLY31
A	ARG32
A	ARG33
A	LEU53

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 A 311

Chain	Residue
A	SER134
A	THR135
A	ALA136
A	TYR141
A	TYR147
A	GLY178
A	PHE185
A	NAP301

---

site_id	AC3
Number of Residues	28
Details	BINDING SITE FOR RESIDUE NAP B 302

Chain	Residue
B	GLY7
B	THR9
B	ALA10
B	GLY11
B	PHE12
B	ARG32
B	ARG33
B	LEU53
B	ASP54
B	VAL55
B	ARG56
B	ASN81
B	ALA82
B	GLY83
B	ILE132
B	GLY133
B	SER134
B	TYR147
B	LYS151
B	PRO177
B	GLY178
B	VAL180
B	THR183
B	GLU184
B	PHE185
B	PO4312
B	HOH1111
B	HOH1182

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 B 312

Chain	Residue
B	SER134
B	ALA136
B	TYR141
B	TYR147
B	GLY178
B	PHE185
B	NAP302
B	HOH1087

---

site_id	AC5
Number of Residues	30
Details	BINDING SITE FOR RESIDUE NAP C 303

Chain	Residue
C	GLY178
C	VAL180
C	THR183
C	GLU184
C	PHE185
C	PO4313
C	HOH1009
C	HOH1017
C	HOH1322
C	GLY7
C	THR9
C	ALA10
C	GLY11
C	PHE12
C	ARG32
C	ARG33
C	LEU53
C	ASP54
C	VAL55
C	ARG56
C	ASN81
C	ALA82
C	GLY83
C	THR105
C	ILE132
C	GLY133
C	SER134
C	TYR147
C	LYS151
C	PRO177

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 C 313

Chain	Residue
C	SER134
C	TYR141
C	TYR147
C	GLY178
C	PHE185
C	NAP303

---

site_id	AC7
Number of Residues	29
Details	BINDING SITE FOR RESIDUE NAP D 304

Chain	Residue
D	GLY7
D	THR9
D	ALA10
D	GLY11
D	PHE12
D	ARG32
D	ARG33
D	LEU53
D	ASP54
D	VAL55
D	ARG56
D	ASN81
D	ALA82
D	GLY83
D	ILE132
D	GLY133
D	SER134
D	TYR147
D	LYS151
D	PRO177
D	GLY178
D	VAL180
D	THR183
D	GLU184
D	PHE185
D	PO4314
D	HOH1109
D	HOH1114
D	HOH1207

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 D 314

Chain	Residue
D	SER134
D	TYR141
D	TYR147
D	GLY178
D	PHE185
D	NAP304

---

site_id	AC9
Number of Residues	27
Details	BINDING SITE FOR RESIDUE NAP E 305

Chain	Residue
E	GLY7
E	THR9
E	ALA10
E	GLY11
E	PHE12
E	ARG32
E	ARG33
E	LEU53
E	ASP54
E	VAL55
E	ARG56
E	ASN81
E	GLY83
E	THR105
E	ILE132
E	GLY133
E	TYR147
E	LYS151
E	PRO177
E	GLY178
E	VAL180
E	THR183
E	GLU184
E	PHE185
E	PO4315
E	HOH1197
E	HOH1271

---

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 E 315

Chain	Residue
E	SER134
E	ALA136
E	TYR141
E	TYR147
E	GLY178
E	PHE185
E	ARG189
E	NAP305

---

site_id	BC2
Number of Residues	30
Details	BINDING SITE FOR RESIDUE NAP F 306

Chain	Residue
F	GLY7
F	THR9
F	ALA10
F	GLY11
F	PHE12
F	ARG32
F	ARG33
F	LEU53
F	ASP54
F	VAL55
F	ARG56
F	ASN81
F	ALA82
F	GLY83
F	THR105
F	ILE132
F	GLY133
F	SER134
F	TYR147
F	LYS151
F	PRO177
F	GLY178
F	VAL180
F	THR183
F	GLU184
F	PHE185
F	PO4316
F	HOH1026
F	HOH1119
F	HOH1142

---

site_id	BC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 F 316

Chain	Residue
F	SER134
F	THR135
F	ALA136
F	TYR141
F	TYR147
F	GLY178
F	PHE185
F	NAP306

---

Functional Information from PROSITE/UniProt

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. StagswpyagGnvYGATKAFVrQFSlNLR

Chain	Residue	Details
A	SER134-ARG162

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