3APB

Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with iodide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0030246	molecular_function	carbohydrate binding
B	0030246	molecular_function	carbohydrate binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 155

Chain	Residue
B	ARG72
B	ARG99

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 156

Chain	Residue
A	GLN47

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 158

Chain	Residue
A	ARG45

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 159

Chain	Residue
A	HIS38
A	ASN145
B	IOD166

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 160

Chain	Residue
A	PRO18
A	GLY142

---

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 161

Chain	Residue
A	ASP112

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 163

Chain	Residue
A	ARG99
A	HOH212

---

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 164

Chain	Residue
A	TYR93
A	ASP94

---

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 165

Chain	Residue
A	ASN10

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 166

Chain	Residue
A	GLY131
A	HOH229

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 167

Chain	Residue
A	PHE19
A	THR22

---

site_id	BC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 155

Chain	Residue
A	ARG72

---

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 156

Chain	Residue
A	SER148

---

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 157

Chain	Residue
B	ARG45
B	GLN47

---

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 159

Chain	Residue
B	HIS38

---

site_id	BC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 160

Chain	Residue
B	THR22

---

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 161

Chain	Residue
B	ARG99
B	HOH202

---

site_id	BC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 162

Chain	Residue
B	ASP112

---

site_id	CC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 164

Chain	Residue
B	GLY142

---

site_id	CC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 165

Chain	Residue
A	HOH254

---

site_id	CC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 166

Chain	Residue
A	IOD159

---

site_id	CC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 167

Chain	Residue
B	GLY131
B	LYS134

---

site_id	CC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 169

Chain	Residue
B	LYS111

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	266
Details	Domain: {"description":"Galectin 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00639","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21288902","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Site: {"description":"Critical for binding to sialylated and sulfated oligosaccharides","evidences":[{"source":"PubMed","id":"21288902","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---