Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3AOU

Structure of the Na+ unbound rotor ring modified with N,N f-Dicyclohexylcarbodiimide of the Na+-transporting V-ATPase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0006814	biological_process	sodium ion transport
A	0015078	molecular_function	proton transmembrane transporter activity
A	0016020	cellular_component	membrane
A	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
A	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
A	0042802	molecular_function	identical protein binding
A	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
A	1902600	biological_process	proton transmembrane transport
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0006814	biological_process	sodium ion transport
B	0015078	molecular_function	proton transmembrane transporter activity
B	0016020	cellular_component	membrane
B	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
B	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
B	0042802	molecular_function	identical protein binding
B	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
B	1902600	biological_process	proton transmembrane transport
C	0005886	cellular_component	plasma membrane
C	0006811	biological_process	monoatomic ion transport
C	0006814	biological_process	sodium ion transport
C	0015078	molecular_function	proton transmembrane transporter activity
C	0016020	cellular_component	membrane
C	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
C	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
C	0042802	molecular_function	identical protein binding
C	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
C	1902600	biological_process	proton transmembrane transport
D	0005886	cellular_component	plasma membrane
D	0006811	biological_process	monoatomic ion transport
D	0006814	biological_process	sodium ion transport
D	0015078	molecular_function	proton transmembrane transporter activity
D	0016020	cellular_component	membrane
D	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
D	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
D	0042802	molecular_function	identical protein binding
D	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
D	1902600	biological_process	proton transmembrane transport
E	0005886	cellular_component	plasma membrane
E	0006811	biological_process	monoatomic ion transport
E	0006814	biological_process	sodium ion transport
E	0015078	molecular_function	proton transmembrane transporter activity
E	0016020	cellular_component	membrane
E	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
E	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
E	0042802	molecular_function	identical protein binding
E	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
E	1902600	biological_process	proton transmembrane transport
F	0005886	cellular_component	plasma membrane
F	0006811	biological_process	monoatomic ion transport
F	0006814	biological_process	sodium ion transport
F	0015078	molecular_function	proton transmembrane transporter activity
F	0016020	cellular_component	membrane
F	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
F	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
F	0042802	molecular_function	identical protein binding
F	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
F	1902600	biological_process	proton transmembrane transport
G	0005886	cellular_component	plasma membrane
G	0006811	biological_process	monoatomic ion transport
G	0006814	biological_process	sodium ion transport
G	0015078	molecular_function	proton transmembrane transporter activity
G	0016020	cellular_component	membrane
G	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
G	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
G	0042802	molecular_function	identical protein binding
G	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
G	1902600	biological_process	proton transmembrane transport
H	0005886	cellular_component	plasma membrane
H	0006811	biological_process	monoatomic ion transport
H	0006814	biological_process	sodium ion transport
H	0015078	molecular_function	proton transmembrane transporter activity
H	0016020	cellular_component	membrane
H	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
H	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
H	0042802	molecular_function	identical protein binding
H	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
H	1902600	biological_process	proton transmembrane transport
I	0005886	cellular_component	plasma membrane
I	0006811	biological_process	monoatomic ion transport
I	0006814	biological_process	sodium ion transport
I	0015078	molecular_function	proton transmembrane transporter activity
I	0016020	cellular_component	membrane
I	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
I	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
I	0042802	molecular_function	identical protein binding
I	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
I	1902600	biological_process	proton transmembrane transport
J	0005886	cellular_component	plasma membrane
J	0006811	biological_process	monoatomic ion transport
J	0006814	biological_process	sodium ion transport
J	0015078	molecular_function	proton transmembrane transporter activity
J	0016020	cellular_component	membrane
J	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
J	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
J	0042802	molecular_function	identical protein binding
J	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
J	1902600	biological_process	proton transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DCW A 201

Chain	Residue
A	ALA136
A	GLU139
A	THR140
A	ILE143

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE DCW B 201

Chain	Residue
B	ALA136
B	GLU139
B	THR140

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DCW C 201

Chain	Residue
C	THR140
C	ILE143
C	ALA136
C	GLU139

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE UMQ C 202

Chain	Residue
C	GLN54
C	PRO125
C	GLU126
C	THR129
F	LYS123
F	LYS124
F	GLU126

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE DCW D 201

Chain	Residue
D	ALA136
D	GLU139
D	THR140

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DCW E 201

Chain	Residue
E	LEU61
E	ALA136
E	GLU139
E	THR140

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE DCW F 201

Chain	Residue
F	ALA136
F	GLU139
F	THR140

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE UMQ F 202

Chain	Residue
C	LYS124
C	GLU126
F	GLN54
F	GLU126
F	THR129

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE DCW G 201

Chain	Residue
G	ALA136
G	GLU139
G	THR140

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DCW H 201

Chain	Residue
H	ALA136
H	GLU139
H	THR140
H	ILE143

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DCW I 201

Chain	Residue
I	ALA136
I	GLU139
I	THR140
I	ILE143

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DCW J 201

Chain	Residue
J	THR64
J	ALA136
J	GLU139
J	THR140

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	800
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)