3ANP
Crystal structure of Thermus thermophilus FadR, a TetR familly transcriptional repressor, in complex with lauroyl-CoA.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0000976 | molecular_function | transcription cis-regulatory region binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0000976 | molecular_function | transcription cis-regulatory region binding |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0000976 | molecular_function | transcription cis-regulatory region binding |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003700 | molecular_function | DNA-binding transcription factor activity |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE DCC D 1000 |
| Chain | Residue |
| C | LEU64 |
| C | HOH692 |
| D | ARG168 |
| D | TYR172 |
| D | THR173 |
| D | ARG176 |
| D | HOH232 |
| D | HOH265 |
| D | HOH589 |
| D | HOH669 |
| D | HOH707 |
| C | LEU111 |
| C | ALA119 |
| C | ARG120 |
| C | PHE123 |
| C | ARG156 |
| C | ASP160 |
| C | PHE163 |
| C | HOH222 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE DCC A 1001 |
| Chain | Residue |
| A | ARG168 |
| A | TYR172 |
| A | THR173 |
| A | ARG176 |
| A | HOH499 |
| A | HOH645 |
| B | LEU111 |
| B | ALA119 |
| B | ARG120 |
| B | PHE123 |
| B | SER150 |
| B | ARG153 |
| B | ASP160 |
| B | TYR162 |
| B | PHE163 |
| D | ARG10 |
| D | ARG11 |
| D | ASN48 |
| D | TYR49 |
| D | HOH557 |
| site_id | AC3 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE DCC A 1002 |
| Chain | Residue |
| A | LEU64 |
| A | LEU111 |
| A | ALA119 |
| A | ARG120 |
| A | PHE123 |
| A | SER150 |
| A | ARG153 |
| A | ARG156 |
| A | ASP160 |
| A | HOH232 |
| A | HOH263 |
| A | HOH400 |
| A | HOH464 |
| A | HOH638 |
| A | HOH684 |
| B | ARG10 |
| B | ARG13 |
| B | ARG168 |
| B | TYR172 |
| B | ARG176 |
| B | ASP177 |
| B | GLU180 |
| B | LYS184 |
| B | HOH243 |
| B | HOH250 |
| B | HOH262 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DAO D 1003 |
| Chain | Residue |
| D | LEU93 |
| D | LEU111 |
| D | PHE123 |
| D | ASP160 |
| D | TYR162 |
| D | PHE163 |
| D | HOH704 |
