3ALL
Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, mutant Y270A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0047081 | molecular_function | 3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity |
| A | 0071949 | molecular_function | FAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0047081 | molecular_function | 3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity |
| B | 0071949 | molecular_function | FAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 33 |
| Details | BINDING SITE FOR RESIDUE FAD A 380 |
| Chain | Residue |
| A | GLY18 |
| A | TYR54 |
| A | ARG106 |
| A | GLU129 |
| A | ALA130 |
| A | ALA155 |
| A | ASP156 |
| A | LEU179 |
| A | ARG181 |
| A | GLY287 |
| A | ASP288 |
| A | GLY20 |
| A | ALA298 |
| A | GLY300 |
| A | ALA301 |
| A | GLY302 |
| A | GOL384 |
| A | HOH387 |
| A | HOH406 |
| A | HOH408 |
| A | HOH411 |
| A | HOH426 |
| A | PHE21 |
| A | HOH428 |
| A | HOH531 |
| A | HOH546 |
| A | HOH594 |
| A | ALA22 |
| A | HIS40 |
| A | GLU41 |
| A | LYS42 |
| A | SER43 |
| A | ILE53 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BME A 381 |
| Chain | Residue |
| A | THR143 |
| A | SER175 |
| A | CYS294 |
| A | ALA347 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 382 |
| Chain | Residue |
| A | GLN74 |
| A | GLY75 |
| A | SER76 |
| A | ASN218 |
| A | GLU219 |
| A | HOH578 |
| B | ASN97 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 383 |
| Chain | Residue |
| A | SER277 |
| A | THR279 |
| A | ARG280 |
| A | GLY281 |
| A | HOH492 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 384 |
| Chain | Residue |
| A | LEU179 |
| A | LEU213 |
| A | TYR223 |
| A | PRO295 |
| A | FAD380 |
| A | HOH490 |
| site_id | AC6 |
| Number of Residues | 33 |
| Details | BINDING SITE FOR RESIDUE FAD B 380 |
| Chain | Residue |
| B | GLY18 |
| B | GLY20 |
| B | PHE21 |
| B | ALA22 |
| B | HIS40 |
| B | GLU41 |
| B | LYS42 |
| B | SER43 |
| B | ILE53 |
| B | TYR54 |
| B | ARG106 |
| B | SER128 |
| B | GLU129 |
| B | ALA130 |
| B | ALA155 |
| B | ASP156 |
| B | ARG181 |
| B | GLY287 |
| B | ASP288 |
| B | PRO295 |
| B | ALA298 |
| B | GLY300 |
| B | ALA301 |
| B | GLY302 |
| B | HOH403 |
| B | HOH408 |
| B | HOH410 |
| B | HOH420 |
| B | HOH428 |
| B | HOH434 |
| B | HOH448 |
| B | HOH455 |
| B | HOH497 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BME B 381 |
| Chain | Residue |
| B | SER175 |
| B | THR272 |
| B | CYS294 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 382 |
| Chain | Residue |
| A | PRO378 |
| A | GLN379 |
| B | GLN74 |
| B | GLY75 |
| B | SER76 |
| B | HIS77 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 383 |
| Chain | Residue |
| B | ASN33 |
| B | GLY34 |
| B | TRP35 |
| B | GLU316 |
| B | THR11 |
| B | ARG12 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19317437","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27568368","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ALJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ALL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ALM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GMC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4GF7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4H2N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4H2P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4H2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4H2R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HXI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27568368","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4JY3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19317437","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3GMC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4H2Q","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19317437","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3GMC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
