3AL5

Crystal structure of Human TYW5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0005506	molecular_function	iron ion binding
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0008033	biological_process	tRNA processing
A	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
A	0031591	biological_process	wybutosine biosynthetic process
A	0042803	molecular_function	protein homodimerization activity
A	0046872	molecular_function	metal ion binding
A	0051213	molecular_function	dioxygenase activity
A	0102524	molecular_function	tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity
B	0000049	molecular_function	tRNA binding
B	0005506	molecular_function	iron ion binding
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0008033	biological_process	tRNA processing
B	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
B	0031591	biological_process	wybutosine biosynthetic process
B	0042803	molecular_function	protein homodimerization activity
B	0046872	molecular_function	metal ion binding
B	0051213	molecular_function	dioxygenase activity
B	0102524	molecular_function	tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity
C	0000049	molecular_function	tRNA binding
C	0005506	molecular_function	iron ion binding
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0008033	biological_process	tRNA processing
C	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
C	0031591	biological_process	wybutosine biosynthetic process
C	0042803	molecular_function	protein homodimerization activity
C	0046872	molecular_function	metal ion binding
C	0051213	molecular_function	dioxygenase activity
C	0102524	molecular_function	tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity
D	0000049	molecular_function	tRNA binding
D	0005506	molecular_function	iron ion binding
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0008033	biological_process	tRNA processing
D	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
D	0031591	biological_process	wybutosine biosynthetic process
D	0042803	molecular_function	protein homodimerization activity
D	0046872	molecular_function	metal ion binding
D	0051213	molecular_function	dioxygenase activity
D	0102524	molecular_function	tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG B 401

Chain	Residue
B	HIS160
B	ASP162
B	HIS235

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 401

Chain	Residue
D	ARG149
D	HIS160
D	ASP162
D	HIS235

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:20972222

Chain	Residue	Details
A	TYR106
D	TYR106
D	ASN166
D	LYS175
A	ASN166
A	LYS175
B	TYR106
B	ASN166
B	LYS175
C	TYR106
C	ASN166
C	LYS175

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING:

Chain	Residue	Details
A	HIS160
D	HIS160
D	ASP162
D	HIS235
A	ASP162
A	HIS235
B	HIS160
B	ASP162
B	HIS235
C	HIS160
C	ASP162
C	HIS235

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