3AKZ

Crystal structure of Thermotoga maritima nondiscriminating glutamyl-tRNA synthetase in complex with tRNAGln and a glutamyl-AMP analog

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0000166	molecular_function	nucleotide binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004818	molecular_function	glutamate-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006424	biological_process	glutamyl-tRNA aminoacylation
A	0008270	molecular_function	zinc ion binding
A	0043039	biological_process	tRNA aminoacylation
B	0000049	molecular_function	tRNA binding
B	0000166	molecular_function	nucleotide binding
B	0004812	molecular_function	aminoacyl-tRNA ligase activity
B	0004818	molecular_function	glutamate-tRNA ligase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006412	biological_process	translation
B	0006418	biological_process	tRNA aminoacylation for protein translation
B	0006424	biological_process	glutamyl-tRNA aminoacylation
B	0008270	molecular_function	zinc ion binding
B	0043039	biological_process	tRNA aminoacylation
C	0000049	molecular_function	tRNA binding
C	0000166	molecular_function	nucleotide binding
C	0004812	molecular_function	aminoacyl-tRNA ligase activity
C	0004818	molecular_function	glutamate-tRNA ligase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006412	biological_process	translation
C	0006418	biological_process	tRNA aminoacylation for protein translation
C	0006424	biological_process	glutamyl-tRNA aminoacylation
C	0008270	molecular_function	zinc ion binding
C	0043039	biological_process	tRNA aminoacylation
D	0000049	molecular_function	tRNA binding
D	0000166	molecular_function	nucleotide binding
D	0004812	molecular_function	aminoacyl-tRNA ligase activity
D	0004818	molecular_function	glutamate-tRNA ligase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006412	biological_process	translation
D	0006418	biological_process	tRNA aminoacylation for protein translation
D	0006424	biological_process	glutamyl-tRNA aminoacylation
D	0008270	molecular_function	zinc ion binding
D	0043039	biological_process	tRNA aminoacylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE GSU B 1001

Chain	Residue
B	ARG28
B	ARG216
B	GLY217
B	ASP219
B	HIS220
B	LEU246
B	ILE247
B	PRO254
B	LEU255
F	A76
B	PHE29
B	ALA30
B	PRO31
B	SER32
B	GLY40
B	GLY41
B	GLU64
B	TYR198

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site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE GSU D 1001

Chain	Residue
D	ARG28
D	PHE29
D	ALA30
D	PRO31
D	SER32
D	HIS38
D	GLY40
D	THR44
D	GLU64
D	TYR198
D	GLY217
D	HIS220
D	LEU246
D	ILE247
H	A76

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site_id	AC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE GSU C 1001

Chain	Residue
C	ARG28
C	PHE29
C	ALA30
C	PRO31
C	SER32
C	GLY40
C	THR44
C	GLU64
C	TYR198
C	ARG216
C	GLY217
C	ASP219
C	HIS220
C	ILE247
C	PRO254
G	A76

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site_id	AC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE GSU A 1001

Chain	Residue
A	ARG28
A	PHE29
A	ALA30
A	PRO31
A	SER32
A	HIS38
A	THR44
A	GLU64
A	TYR198
A	ARG216
A	GLY217
A	ASP219
A	HIS220
A	LEU246
A	ILE247
A	LEU255
E	A76

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Functional Information from PROSITE/UniProt

site_id	PS00178
Number of Residues	12
Details	AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. PspTGhLHVGGA

Chain	Residue	Details
B	PRO31-ALA42

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00022

Chain	Residue	Details
B	LYS257
D	LYS257
C	LYS257
A	LYS257

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