3AKZ
Crystal structure of Thermotoga maritima nondiscriminating glutamyl-tRNA synthetase in complex with tRNAGln and a glutamyl-AMP analog
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004818 | molecular_function | glutamate-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006424 | biological_process | glutamyl-tRNA aminoacylation |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0043039 | biological_process | tRNA aminoacylation |
| B | 0000049 | molecular_function | tRNA binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004818 | molecular_function | glutamate-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006424 | biological_process | glutamyl-tRNA aminoacylation |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0043039 | biological_process | tRNA aminoacylation |
| C | 0000049 | molecular_function | tRNA binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| C | 0004818 | molecular_function | glutamate-tRNA ligase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| C | 0006424 | biological_process | glutamyl-tRNA aminoacylation |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0043039 | biological_process | tRNA aminoacylation |
| D | 0000049 | molecular_function | tRNA binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| D | 0004818 | molecular_function | glutamate-tRNA ligase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| D | 0006424 | biological_process | glutamyl-tRNA aminoacylation |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0043039 | biological_process | tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE GSU B 1001 |
| Chain | Residue |
| B | ARG28 |
| B | ARG216 |
| B | GLY217 |
| B | ASP219 |
| B | HIS220 |
| B | LEU246 |
| B | ILE247 |
| B | PRO254 |
| B | LEU255 |
| F | A76 |
| B | PHE29 |
| B | ALA30 |
| B | PRO31 |
| B | SER32 |
| B | GLY40 |
| B | GLY41 |
| B | GLU64 |
| B | TYR198 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE GSU D 1001 |
| Chain | Residue |
| D | ARG28 |
| D | PHE29 |
| D | ALA30 |
| D | PRO31 |
| D | SER32 |
| D | HIS38 |
| D | GLY40 |
| D | THR44 |
| D | GLU64 |
| D | TYR198 |
| D | GLY217 |
| D | HIS220 |
| D | LEU246 |
| D | ILE247 |
| H | A76 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GSU C 1001 |
| Chain | Residue |
| C | ARG28 |
| C | PHE29 |
| C | ALA30 |
| C | PRO31 |
| C | SER32 |
| C | GLY40 |
| C | THR44 |
| C | GLU64 |
| C | TYR198 |
| C | ARG216 |
| C | GLY217 |
| C | ASP219 |
| C | HIS220 |
| C | ILE247 |
| C | PRO254 |
| G | A76 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GSU A 1001 |
| Chain | Residue |
| A | ARG28 |
| A | PHE29 |
| A | ALA30 |
| A | PRO31 |
| A | SER32 |
| A | HIS38 |
| A | THR44 |
| A | GLU64 |
| A | TYR198 |
| A | ARG216 |
| A | GLY217 |
| A | ASP219 |
| A | HIS220 |
| A | LEU246 |
| A | ILE247 |
| A | LEU255 |
| E | A76 |
Functional Information from PROSITE/UniProt
| site_id | PS00178 |
| Number of Residues | 12 |
| Details | AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. PspTGhLHVGGA |
| Chain | Residue | Details |
| B | PRO31-ALA42 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Motif: {"description":"'HIGH' region","evidences":[{"source":"HAMAP-Rule","id":"MF_00022","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Motif: {"description":"'KMSKS' region","evidences":[{"source":"HAMAP-Rule","id":"MF_00022","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00022","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
