3AK4
Crystal structure of NADH-dependent quinuclidinone reductase from agrobacterium tumefaciens
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0048038 | molecular_function | quinone binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0048038 | molecular_function | quinone binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0006633 | biological_process | fatty acid biosynthetic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| C | 0048038 | molecular_function | quinone binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0006633 | biological_process | fatty acid biosynthetic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| D | 0048038 | molecular_function | quinone binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NAD A 901 |
| Chain | Residue |
| A | GLY16 |
| A | VAL64 |
| A | ASN90 |
| A | GLY92 |
| A | THR141 |
| A | ALA142 |
| A | SER143 |
| A | TYR156 |
| A | LYS160 |
| A | GLY187 |
| A | VAL189 |
| A | SER18 |
| A | THR191 |
| A | MET193 |
| A | ARG196 |
| A | HOH276 |
| A | HOH281 |
| A | HOH283 |
| A | HOH291 |
| A | HOH301 |
| A | HOH413 |
| A | LYS19 |
| A | GLY20 |
| A | ILE21 |
| A | ASP40 |
| A | LEU41 |
| A | VAL62 |
| A | ASP63 |
| site_id | AC2 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE NAD B 902 |
| Chain | Residue |
| B | GLY16 |
| B | LYS19 |
| B | GLY20 |
| B | ILE21 |
| B | ASP40 |
| B | LEU41 |
| B | VAL62 |
| B | ASP63 |
| B | VAL64 |
| B | ASN90 |
| B | GLY92 |
| B | THR141 |
| B | ALA142 |
| B | SER143 |
| B | TYR156 |
| B | LYS160 |
| B | PRO186 |
| B | GLY187 |
| B | VAL189 |
| B | THR191 |
| B | MET193 |
| B | ARG196 |
| B | HOH282 |
| B | HOH310 |
| B | HOH333 |
| B | HOH347 |
| B | HOH404 |
| site_id | AC3 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE NAD C 903 |
| Chain | Residue |
| C | GLY16 |
| C | SER18 |
| C | LYS19 |
| C | GLY20 |
| C | ILE21 |
| C | ASP40 |
| C | LEU41 |
| C | VAL62 |
| C | ASP63 |
| C | VAL64 |
| C | ASN90 |
| C | ALA91 |
| C | GLY92 |
| C | THR141 |
| C | ALA142 |
| C | SER143 |
| C | TYR156 |
| C | LYS160 |
| C | PRO186 |
| C | GLY187 |
| C | VAL189 |
| C | THR191 |
| C | MET193 |
| C | ARG196 |
| C | HOH267 |
| C | HOH271 |
| C | HOH274 |
| C | HOH299 |
| C | HOH302 |
| C | HOH311 |
| C | HOH490 |
| site_id | AC4 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE NAD D 904 |
| Chain | Residue |
| D | THR141 |
| D | ALA142 |
| D | SER143 |
| D | TYR156 |
| D | LYS160 |
| D | PRO186 |
| D | GLY187 |
| D | VAL189 |
| D | THR191 |
| D | MET193 |
| D | ARG196 |
| D | HOH280 |
| D | HOH289 |
| D | HOH304 |
| D | HOH390 |
| D | HOH661 |
| D | GLY16 |
| D | SER18 |
| D | LYS19 |
| D | GLY20 |
| D | ILE21 |
| D | ASP40 |
| D | LEU41 |
| D | VAL62 |
| D | ASP63 |
| D | VAL64 |
| D | ASN90 |
| D | ALA91 |
| D | GLY92 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. SlaakvgaplLahYSASKFAVfGWTqALA |
| Chain | Residue | Details |
| A | SER143-ALA171 |
