3AJ8

X-ray analysis of Crystal of Proteinase K Obtained from H2O Solution Using PEG 8000

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004252	molecular_function	serine-type endopeptidase activity
A	0006508	biological_process	proteolysis
A	0008236	molecular_function	serine-type peptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A 384

Chain	Residue
A	PRO175
A	VAL177
A	ASP200
A	HOH402
A	HOH412
A	HOH425
A	HOH428

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 385

Chain	Residue
A	HOH461
A	HOH481
A	HOH508
A	HOH554
A	THR16
A	ASP260

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL A 386

Chain	Residue
A	ARG188
A	ARG189
A	LYS242
A	THR243
A	SER247
A	TYR251
A	ASN263
A	HOH363
A	HOH414
A	HOH416

---

Functional Information from PROSITE/UniProt

site_id	PS00136
Number of Residues	12
Details	SUBTILASE_ASP Serine proteases, subtilase family, aspartic acid active site. VYVIDTGIeasH

Chain	Residue	Details
A	VAL35-HIS46

---

site_id	PS00137
Number of Residues	11
Details	SUBTILASE_HIS Serine proteases, subtilase family, histidine active site. HGThCAGtVGS

Chain	Residue	Details
A	HIS69-SER79

---

site_id	PS00138
Number of Residues	11
Details	SUBTILASE_SER Serine proteases, subtilase family, serine active site. GTSmAtPhVAG

Chain	Residue	Details
A	GLY222-GLY232

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	272
Details	Domain: {"description":"Peptidase S8","evidences":[{"source":"PROSITE-ProRule","id":"PRU01240","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"PROSITE-ProRule","id":"PRU01240","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	5
Details	Binding site: {}

Chain

Residue

Details

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