Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004222 | molecular_function | metalloendopeptidase activity |
A | 0005576 | cellular_component | extracellular region |
A | 0005886 | cellular_component | plasma membrane |
A | 0006508 | biological_process | proteolysis |
A | 0008237 | molecular_function | metallopeptidase activity |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 999 |
Chain | Residue |
A | HIS142 |
A | HIS146 |
A | HIS152 |
A | 0ZC1000 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 250 |
Chain | Residue |
A | HOH307 |
A | GLU9 |
A | ASP93 |
A | GLN196 |
A | CYS197 |
A | ASN200 |
site_id | AC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 260 |
Chain | Residue |
A | ARG6 |
A | HOH354 |
A | HOH359 |
site_id | AC4 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE 0ZC A 1000 |
Chain | Residue |
A | GLY105 |
A | LYS106 |
A | ILE107 |
A | ILE108 |
A | GLY109 |
A | THR139 |
A | HIS142 |
A | GLU143 |
A | HIS152 |
A | ILE165 |
A | ARG167 |
A | PRO168 |
A | GLY169 |
A | LEU170 |
A | ZN999 |
Functional Information from PROSITE/UniProt
site_id | PS00142 |
Number of Residues | 10 |
Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TMAHELGHNL |
Chain | Residue | Details |
A | THR139-LEU148 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | GLU143 | |
Chain | Residue | Details |
A | GLU9 | |
A | ASP93 | |
A | CYS197 | |
A | ASN200 | |
site_id | SWS_FT_FI3 |
Number of Residues | 3 |
Details | BINDING: |
Chain | Residue | Details |
A | HIS142 | |
A | HIS146 | |
A | HIS152 | |