3AF6
The crystal structure of an archaeal CPSF subunit, PH1404 from Pyrococcus horikoshii complexed with RNA-analog
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004521 | molecular_function | RNA endonuclease activity |
| A | 0004527 | molecular_function | exonuclease activity |
| A | 0004532 | molecular_function | RNA exonuclease activity |
| A | 0006353 | biological_process | DNA-templated transcription termination |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 652 |
| Chain | Residue |
| A | ARG202 |
| A | TYR229 |
| A | HIS234 |
| A | ASN644 |
| A | ARG649 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 653 |
| Chain | Residue |
| A | TYR242 |
| A | THR209 |
| A | PHE213 |
| A | ASP236 |
| A | PRO238 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 654 |
| Chain | Residue |
| A | TYR325 |
| A | ASN341 |
| A | GLU377 |
| A | GLU474 |
| A | TYR475 |
| A | LEU476 |
| A | GLU573 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 655 |
| Chain | Residue |
| A | ASP260 |
| A | ASP367 |
| A | TYR550 |
| A | HIS594 |
| A | HIS618 |
| A | ZN658 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 656 |
| Chain | Residue |
| A | ASP324 |
| A | TYR325 |
| A | GLU474 |
| A | GLU573 |
| A | GLY574 |
| A | ARG575 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 657 |
| Chain | Residue |
| A | HIS256 |
| A | HIS258 |
| A | HIS344 |
| A | ASP367 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 658 |
| Chain | Residue |
| A | ASP260 |
| A | HIS261 |
| A | ASP367 |
| A | HIS618 |
| A | SO4655 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 67 |
| Details | Region: {"description":"KHb","evidences":[{"source":"HAMAP-Rule","id":"MF_00870","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20544974","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 210 |
| Details | Region: {"description":"Metallo-beta-lactamase N-terminus","evidences":[{"source":"HAMAP-Rule","id":"MF_00870","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 193 |
| Details | Region: {"description":"Beta-Casp","evidences":[{"source":"HAMAP-Rule","id":"MF_00870","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 58 |
| Details | Region: {"description":"Metallo-beta-lactamase C-terminus","evidences":[{"source":"HAMAP-Rule","id":"MF_00870","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00870","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20544974","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3AF5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AF6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
