3AF6

The crystal structure of an archaeal CPSF subunit, PH1404 from Pyrococcus horikoshii complexed with RNA-analog

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003723	molecular_function	RNA binding
A	0004519	molecular_function	endonuclease activity
A	0004521	molecular_function	RNA endonuclease activity
A	0004527	molecular_function	exonuclease activity
A	0006353	biological_process	DNA-templated transcription termination
A	0008270	molecular_function	zinc ion binding
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 652

Chain	Residue
A	ARG202
A	TYR229
A	HIS234
A	ASN644
A	ARG649

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 653

Chain	Residue
A	TYR242
A	THR209
A	PHE213
A	ASP236
A	PRO238

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 654

Chain	Residue
A	TYR325
A	ASN341
A	GLU377
A	GLU474
A	TYR475
A	LEU476
A	GLU573

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 655

Chain	Residue
A	ASP260
A	ASP367
A	TYR550
A	HIS594
A	HIS618
A	ZN658

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 656

Chain	Residue
A	ASP324
A	TYR325
A	GLU474
A	GLU573
A	GLY574
A	ARG575

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 657

Chain	Residue
A	HIS256
A	HIS258
A	HIS344
A	ASP367

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 658

Chain	Residue
A	ASP260
A	HIS261
A	ASP367
A	HIS618
A	SO4655

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00870, ECO:0000269|PubMed:20544974, ECO:0007744|PDB:3AF5, ECO:0007744|PDB:3AF6

Chain	Residue	Details
A	HIS256
A	HIS258
A	ASP260
A	HIS261
A	HIS344
A	ASP367
A	HIS618

---