3AF1

Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with GDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004594	molecular_function	pantothenate kinase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0015937	biological_process	coenzyme A biosynthetic process
A	0016301	molecular_function	kinase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE GDP A 313

Chain	Residue
A	SER98
A	MET242
A	ALA246
A	HOH331
A	HOH333
A	HOH439
A	HOH515
A	HOH531
A	VAL99
A	ALA100
A	VAL101
A	GLY102
A	LYS103
A	SER104
A	HIS179
A	ARG238

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FLC A 314

Chain	Residue
A	ASP129
A	TYR177
A	SER178
A	HIS179
A	LEU180
A	HOH531
A	HOH532

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 315

Chain	Residue
A	ARG270

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 316

Chain	Residue
A	THR128
A	ASN204

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 317

Chain	Residue
A	GLN207
A	HOH395

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 318

Chain	Residue
A	GLN207
A	THR208
A	GLY209
A	PRO210
A	PRO287
A	ARG291

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 319

Chain	Residue
A	ARG15
A	GLN43
A	GLU48
A	ASP301
A	SER303
A	HOH389

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 320

Chain	Residue
A	GLU189
A	ALA248
A	HIS255

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 321

Chain	Residue
A	ASP225
A	ALA226
A	ARG289
A	ARG297

---

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 322

Chain	Residue
A	PHE218
A	SER221
A	ARG291
A	THR293
A	ARG310
A	GOL330
A	HOH351

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 323

Chain	Residue
A	SER215
A	ASP216
A	ARG310
A	GOL330
A	HOH351
A	HOH498

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 324

Chain	Residue
A	ALA157
A	PHE161
A	CYS173
A	HOH406

---

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 325

Chain	Residue
A	ARG122
A	HIS194
A	HOH428

---

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 326

Chain	Residue
A	GLY41
A	ALA136
A	SER237
A	ARG238
A	ALA241
A	HOH359

---

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 327

Chain	Residue
A	GLN111
A	ARG122
A	VAL123

---

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 328

Chain	Residue
A	ARG146
A	PHE149
A	GLU151
A	GLU283
A	ASN284

---

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 329

Chain	Residue
A	GLY36
A	ARG38
A	ARG108
A	HOH333

---

site_id	BC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 330

Chain	Residue
A	ARG67
A	LYS166
A	ASP216
A	PHE218
A	ASP219
A	LEU312
A	GOL322
A	GOL323

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	GLY97

---