3AEX
Catalytic intermediate analogue of threonine synthase from Thermus thermophilus HB8
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004795 | molecular_function | threonine synthase activity |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0009088 | biological_process | threonine biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 1901605 | biological_process | alpha-amino acid metabolic process |
| B | 0004795 | molecular_function | threonine synthase activity |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0009088 | biological_process | threonine biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 1901605 | biological_process | alpha-amino acid metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE AN7 A 1001 |
| Chain | Residue |
| A | PHE60 |
| A | GLY187 |
| A | ASN188 |
| A | ALA189 |
| A | GLY190 |
| A | ASN191 |
| A | ALA240 |
| A | ILE241 |
| A | GLU287 |
| A | THR317 |
| A | HOH365 |
| A | LYS61 |
| A | HOH377 |
| A | HOH388 |
| A | HOH392 |
| A | HOH430 |
| A | PO46265 |
| A | SER84 |
| A | THR85 |
| A | GLY86 |
| A | ASN87 |
| A | THR88 |
| A | PHE134 |
| A | VAL186 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 A 6265 |
| Chain | Residue |
| A | LYS61 |
| A | THR88 |
| A | ASN154 |
| A | SER155 |
| A | ARG160 |
| A | ASN188 |
| A | HOH365 |
| A | AN71001 |
| site_id | AC3 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE AN7 B 1002 |
| Chain | Residue |
| B | PHE60 |
| B | LYS61 |
| B | SER84 |
| B | THR85 |
| B | GLY86 |
| B | ASN87 |
| B | THR88 |
| B | PHE134 |
| B | VAL186 |
| B | GLY187 |
| B | ASN188 |
| B | ALA189 |
| B | GLY190 |
| B | ASN191 |
| B | ALA240 |
| B | ILE241 |
| B | GLU287 |
| B | THR317 |
| B | GLY318 |
| B | HOH356 |
| B | HOH360 |
| B | HOH368 |
| B | HOH381 |
| B | HOH429 |
| B | PO46267 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 B 6267 |
| Chain | Residue |
| B | LYS61 |
| B | THR88 |
| B | PHE134 |
| B | ASN154 |
| B | SER155 |
| B | ARG160 |
| B | ASN188 |
| B | HOH356 |
| B | AN71002 |
Functional Information from PROSITE/UniProt
| site_id | PS00165 |
| Number of Residues | 14 |
| Details | DEHYDRATASE_SER_THR Serine/threonine dehydratases pyridoxal-phosphate attachment site. Eglnp.TGSFKDRGM |
| Chain | Residue | Details |
| A | GLU52-MET65 |
