3ADP
Crystal Structure of the Rabbit L-Gulonate 3-Dehydrogenase (NADH Form)
Replaces: 3A97Replaces: 2EP9Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005212 | molecular_function | structural constituent of eye lens |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0050104 | molecular_function | L-gulonate 3-dehydrogenase activity |
| A | 0070403 | molecular_function | NAD+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAI A 1001 |
| Chain | Residue |
| A | GLY15 |
| A | GLU97 |
| A | LYS102 |
| A | ILE105 |
| A | SER122 |
| A | SER124 |
| A | HIS145 |
| A | PRO146 |
| A | ASN148 |
| A | HOH328 |
| A | HOH361 |
| A | LEU16 |
| A | HOH367 |
| A | HOH428 |
| A | HOH461 |
| A | HOH489 |
| A | HOH504 |
| A | HOH518 |
| A | HOH545 |
| A | HOH597 |
| A | HOH632 |
| A | HOH643 |
| A | VAL17 |
| A | HOH644 |
| A | ASP36 |
| A | ILE37 |
| A | GLN41 |
| A | CYS94 |
| A | VAL95 |
| A | PRO96 |
Functional Information from PROSITE/UniProt
| site_id | PS00067 |
| Number of Residues | 25 |
| Details | 3HCDH 3-hydroxyacyl-CoA dehydrogenase signature. EidGFVlNRlqyAIIseawr.LVeeG |
| Chain | Residue | Details |
| A | GLU189-GLY213 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"NOV-2006","submissionDatabase":"PDB data bank","title":"Crystal structure of the rabbit L-gulonate 3-dehydrogenase.","authoringGroup":["RIKEN structural genomics initiative (RSGI)"]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9Y2S2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
