3AD8
Heterotetrameric Sarcosine Oxidase from Corynebacterium sp. U-96 in complex with pyrrole 2-carboxylate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008115 | molecular_function | sarcosine oxidase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046653 | biological_process | tetrahydrofolate metabolic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008115 | molecular_function | sarcosine oxidase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046653 | biological_process | tetrahydrofolate metabolic process |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008115 | molecular_function | sarcosine oxidase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 1901053 | biological_process | sarcosine catabolic process |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008115 | molecular_function | sarcosine oxidase activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0046653 | biological_process | tetrahydrofolate metabolic process |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE NAD A 965 |
| Chain | Residue |
| A | GLY134 |
| A | THR202 |
| A | THR203 |
| A | VAL204 |
| A | ALA247 |
| A | THR248 |
| A | ALA249 |
| A | SER294 |
| A | PHE380 |
| A | LEU386 |
| A | GLY416 |
| A | GLY136 |
| A | ALA417 |
| A | LEU422 |
| A | ASP423 |
| A | THR424 |
| A | TYR553 |
| A | HOH972 |
| A | HOH978 |
| A | HOH1010 |
| A | HOH1022 |
| A | HOH1133 |
| A | PRO137 |
| A | HOH1148 |
| A | HOH1312 |
| A | ALA138 |
| A | ASP157 |
| A | GLU158 |
| A | ARG159 |
| A | GLY164 |
| A | THR165 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2500 |
| Chain | Residue |
| A | ARG597 |
| A | LEU631 |
| A | THR692 |
| A | THR693 |
| A | HOH1596 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2501 |
| Chain | Residue |
| A | ASN651 |
| A | GLY652 |
| A | SER847 |
| A | LEU849 |
| A | HOH1529 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2502 |
| Chain | Residue |
| A | SER7 |
| A | ALA8 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2504 |
| Chain | Residue |
| A | GLN217 |
| A | ARG219 |
| A | HOH1154 |
| A | HOH1214 |
| A | HOH1378 |
| C | VAL199 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2506 |
| Chain | Residue |
| A | ARG686 |
| A | HOH1199 |
| C | GLN102 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2507 |
| Chain | Residue |
| A | ARG929 |
| A | ASN930 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2509 |
| Chain | Residue |
| A | ARG574 |
| A | ALA696 |
| A | ALA697 |
| A | THR722 |
| A | HOH1574 |
| C | ARG176 |
| site_id | AC9 |
| Number of Residues | 40 |
| Details | BINDING SITE FOR RESIDUE FAD B 405 |
| Chain | Residue |
| B | HOH906 |
| B | VAL26 |
| B | GLY27 |
| B | GLY29 |
| B | GLY30 |
| B | HIS31 |
| B | LEU51 |
| B | GLU52 |
| B | LYS53 |
| B | GLY59 |
| B | ASN60 |
| B | MET61 |
| B | ARG63 |
| B | ASN64 |
| B | THR65 |
| B | THR66 |
| B | ILE67 |
| B | CYS194 |
| B | GLU195 |
| B | VAL196 |
| B | ALA224 |
| B | GLY225 |
| B | ALA226 |
| B | HIS228 |
| B | LEU232 |
| B | LEU247 |
| B | GLY326 |
| B | GLY353 |
| B | THR354 |
| B | GLY355 |
| B | GLY356 |
| B | PHE357 |
| B | LYS358 |
| B | HOH412 |
| B | HOH420 |
| B | HOH475 |
| B | HOH605 |
| B | HOH654 |
| B | PYC801 |
| B | HOH862 |
| site_id | BC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE FMN B 406 |
| Chain | Residue |
| A | LYS509 |
| A | ARG510 |
| A | THR516 |
| A | GLN520 |
| A | THR548 |
| A | ARG550 |
| A | HOH1030 |
| B | ALA62 |
| B | ARG63 |
| B | ASN64 |
| B | THR66 |
| B | HIS172 |
| B | VAL251 |
| B | LYS277 |
| B | GLU279 |
| B | ARG322 |
| B | TRP324 |
| B | HOH437 |
| B | HOH450 |
| B | HOH495 |
| B | HOH534 |
| B | HOH544 |
| site_id | BC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PYC B 801 |
| Chain | Residue |
| B | THR65 |
| B | ILE67 |
| B | ARG69 |
| B | TYR72 |
| B | MET264 |
| B | TYR271 |
| B | THR354 |
| B | GLY355 |
| B | LYS358 |
| B | VAL402 |
| B | FAD405 |
| B | HOH423 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2505 |
| Chain | Residue |
| B | ASN13 |
| B | ASN14 |
| B | HOH458 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2510 |
| Chain | Residue |
| B | PRO8 |
| B | GLU9 |
| B | PHE10 |
| B | ARG181 |
| B | HOH599 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2511 |
| Chain | Residue |
| B | LYS171 |
| B | HIS174 |
| B | LYS277 |
| B | HOH426 |
| B | HOH848 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 2508 |
| Chain | Residue |
| A | GLN30 |
| C | ALA25 |
| C | GLY26 |
| C | GLU27 |
| C | ARG28 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 100 |
| Chain | Residue |
| D | CYS6 |
| D | CYS9 |
| D | HIS59 |
| D | CYS63 |
| site_id | BC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 D 2503 |
| Chain | Residue |
| D | ARG83 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15946648","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20675294","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1VRQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1X31","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AD7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AD8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AD9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ADA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15946648","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1VRQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Tele-8alpha-FMN histidine","evidences":[{"source":"PubMed","id":"11902668","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20675294","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3AD7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AD8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AD9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ADA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
