3AD8
Heterotetrameric Sarcosine Oxidase from Corynebacterium sp. U-96 in complex with pyrrole 2-carboxylate
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0008115 | molecular_function | sarcosine oxidase activity |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0046653 | biological_process | tetrahydrofolate metabolic process |
B | 0000166 | molecular_function | nucleotide binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0008115 | molecular_function | sarcosine oxidase activity |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0046653 | biological_process | tetrahydrofolate metabolic process |
C | 0005737 | cellular_component | cytoplasm |
C | 0008115 | molecular_function | sarcosine oxidase activity |
C | 0016491 | molecular_function | oxidoreductase activity |
C | 1901053 | biological_process | sarcosine catabolic process |
D | 0005737 | cellular_component | cytoplasm |
D | 0008115 | molecular_function | sarcosine oxidase activity |
D | 0016491 | molecular_function | oxidoreductase activity |
D | 0046653 | biological_process | tetrahydrofolate metabolic process |
D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 31 |
Details | BINDING SITE FOR RESIDUE NAD A 965 |
Chain | Residue |
A | GLY134 |
A | THR202 |
A | THR203 |
A | VAL204 |
A | ALA247 |
A | THR248 |
A | ALA249 |
A | SER294 |
A | PHE380 |
A | LEU386 |
A | GLY416 |
A | GLY136 |
A | ALA417 |
A | LEU422 |
A | ASP423 |
A | THR424 |
A | TYR553 |
A | HOH972 |
A | HOH978 |
A | HOH1010 |
A | HOH1022 |
A | HOH1133 |
A | PRO137 |
A | HOH1148 |
A | HOH1312 |
A | ALA138 |
A | ASP157 |
A | GLU158 |
A | ARG159 |
A | GLY164 |
A | THR165 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 2500 |
Chain | Residue |
A | ARG597 |
A | LEU631 |
A | THR692 |
A | THR693 |
A | HOH1596 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 2501 |
Chain | Residue |
A | ASN651 |
A | GLY652 |
A | SER847 |
A | LEU849 |
A | HOH1529 |
site_id | AC4 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE SO4 A 2502 |
Chain | Residue |
A | SER7 |
A | ALA8 |
site_id | AC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 2504 |
Chain | Residue |
A | GLN217 |
A | ARG219 |
A | HOH1154 |
A | HOH1214 |
A | HOH1378 |
C | VAL199 |
site_id | AC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 2506 |
Chain | Residue |
A | ARG686 |
A | HOH1199 |
C | GLN102 |
site_id | AC7 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE SO4 A 2507 |
Chain | Residue |
A | ARG929 |
A | ASN930 |
site_id | AC8 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 2509 |
Chain | Residue |
A | ARG574 |
A | ALA696 |
A | ALA697 |
A | THR722 |
A | HOH1574 |
C | ARG176 |
site_id | AC9 |
Number of Residues | 40 |
Details | BINDING SITE FOR RESIDUE FAD B 405 |
Chain | Residue |
B | HOH906 |
B | VAL26 |
B | GLY27 |
B | GLY29 |
B | GLY30 |
B | HIS31 |
B | LEU51 |
B | GLU52 |
B | LYS53 |
B | GLY59 |
B | ASN60 |
B | MET61 |
B | ARG63 |
B | ASN64 |
B | THR65 |
B | THR66 |
B | ILE67 |
B | CYS194 |
B | GLU195 |
B | VAL196 |
B | ALA224 |
B | GLY225 |
B | ALA226 |
B | HIS228 |
B | LEU232 |
B | LEU247 |
B | GLY326 |
B | GLY353 |
B | THR354 |
B | GLY355 |
B | GLY356 |
B | PHE357 |
B | LYS358 |
B | HOH412 |
B | HOH420 |
B | HOH475 |
B | HOH605 |
B | HOH654 |
B | PYC801 |
B | HOH862 |
site_id | BC1 |
Number of Residues | 22 |
Details | BINDING SITE FOR RESIDUE FMN B 406 |
Chain | Residue |
A | LYS509 |
A | ARG510 |
A | THR516 |
A | GLN520 |
A | THR548 |
A | ARG550 |
A | HOH1030 |
B | ALA62 |
B | ARG63 |
B | ASN64 |
B | THR66 |
B | HIS172 |
B | VAL251 |
B | LYS277 |
B | GLU279 |
B | ARG322 |
B | TRP324 |
B | HOH437 |
B | HOH450 |
B | HOH495 |
B | HOH534 |
B | HOH544 |
site_id | BC2 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE PYC B 801 |
Chain | Residue |
B | THR65 |
B | ILE67 |
B | ARG69 |
B | TYR72 |
B | MET264 |
B | TYR271 |
B | THR354 |
B | GLY355 |
B | LYS358 |
B | VAL402 |
B | FAD405 |
B | HOH423 |
site_id | BC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 B 2505 |
Chain | Residue |
B | ASN13 |
B | ASN14 |
B | HOH458 |
site_id | BC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 B 2510 |
Chain | Residue |
B | PRO8 |
B | GLU9 |
B | PHE10 |
B | ARG181 |
B | HOH599 |
site_id | BC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 B 2511 |
Chain | Residue |
B | LYS171 |
B | HIS174 |
B | LYS277 |
B | HOH426 |
B | HOH848 |
site_id | BC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 C 2508 |
Chain | Residue |
A | GLN30 |
C | ALA25 |
C | GLY26 |
C | GLU27 |
C | ARG28 |
site_id | BC7 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN D 100 |
Chain | Residue |
D | CYS6 |
D | CYS9 |
D | HIS59 |
D | CYS63 |
site_id | BC8 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE SO4 D 2503 |
Chain | Residue |
D | ARG83 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:15946648, ECO:0000269|PubMed:20675294, ECO:0007744|PDB:1VRQ, ECO:0007744|PDB:1X31, ECO:0007744|PDB:3AD7, ECO:0007744|PDB:3AD8, ECO:0007744|PDB:3AD9, ECO:0007744|PDB:3ADA |
Chain | Residue | Details |
D | CYS6 | |
B | GLY356 | |
B | LYS358 | |
D | CYS9 | |
D | HIS59 | |
D | CYS63 | |
B | MET61 | |
B | THR65 | |
B | ILE67 | |
B | VAL196 | |
B | GLY353 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | MOD_RES: Tele-8alpha-FMN histidine => ECO:0000269|PubMed:11902668, ECO:0000269|PubMed:20675294, ECO:0007744|PDB:3AD7, ECO:0007744|PDB:3AD8, ECO:0007744|PDB:3AD9, ECO:0007744|PDB:3ADA |
Chain | Residue | Details |
B | HIS172 | |
A | GLU783 |