3ACZ
Crystal structure of Entamoeba histolytica methionine gamma-lyase 1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016846 | molecular_function | carbon-sulfur lyase activity |
| A | 0018826 | molecular_function | methionine gamma-lyase activity |
| A | 0019346 | biological_process | transsulfuration |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016846 | molecular_function | carbon-sulfur lyase activity |
| B | 0018826 | molecular_function | methionine gamma-lyase activity |
| B | 0019346 | biological_process | transsulfuration |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016829 | molecular_function | lyase activity |
| C | 0016846 | molecular_function | carbon-sulfur lyase activity |
| C | 0018826 | molecular_function | methionine gamma-lyase activity |
| C | 0019346 | biological_process | transsulfuration |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0016829 | molecular_function | lyase activity |
| D | 0016846 | molecular_function | carbon-sulfur lyase activity |
| D | 0018826 | molecular_function | methionine gamma-lyase activity |
| D | 0019346 | biological_process | transsulfuration |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2001 |
| Chain | Residue |
| A | TYR108 |
| A | ASN155 |
| A | LLP205 |
| A | VAL331 |
| A | SER332 |
| A | THR347 |
| A | ARG367 |
| A | HOH3593 |
| A | HOH4002 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 C 2002 |
| Chain | Residue |
| A | HIS22 |
| A | ALA23 |
| A | HOH3310 |
| C | HIS1210 |
| C | CYS1335 |
| C | ASP1337 |
| C | HOH3551 |
| C | HOH3906 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2003 |
| Chain | Residue |
| A | ARG176 |
| A | HOH3465 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2004 |
| Chain | Residue |
| B | TYR608 |
| B | ASN655 |
| B | LLP705 |
| B | VAL831 |
| B | SER832 |
| B | LEU833 |
| B | THR847 |
| B | ARG867 |
| B | HOH3623 |
| B | HOH3881 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2005 |
| Chain | Residue |
| B | HIS710 |
| B | CYS835 |
| B | VAL836 |
| B | ASP837 |
| B | HOH3701 |
| D | HIS1522 |
| D | LYS1753 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2006 |
| Chain | Residue |
| B | ARG676 |
| B | HOH3277 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 C 2007 |
| Chain | Residue |
| C | TYR1108 |
| C | ASN1155 |
| C | LLP1205 |
| C | VAL1331 |
| C | SER1332 |
| C | THR1347 |
| C | ARG1367 |
| C | HOH4005 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 D 2008 |
| Chain | Residue |
| B | HIS522 |
| B | ALA523 |
| B | LYS753 |
| B | HOH3582 |
| D | HIS1710 |
| D | CYS1835 |
| D | VAL1836 |
| D | ASP1837 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 2009 |
| Chain | Residue |
| C | ARG1176 |
| C | HOH3591 |
| C | HOH3986 |
| site_id | BC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 D 2010 |
| Chain | Residue |
| D | TYR1608 |
| D | ASN1655 |
| D | LLP1705 |
| D | VAL1831 |
| D | SER1832 |
| D | LEU1833 |
| D | THR1847 |
| D | ARG1867 |
| D | HOH3605 |
| D | HOH3933 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2011 |
| Chain | Residue |
| A | HIS210 |
| A | CYS335 |
| A | VAL336 |
| A | ASP337 |
| A | HOH3259 |
| A | HOH3698 |
| C | ALA1023 |
| C | LYS1253 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 D 2012 |
| Chain | Residue |
| D | ARG1676 |
| site_id | BC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL A 2013 |
| Chain | Residue |
| A | HOH3476 |
| site_id | BC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL C 2014 |
| Chain | Residue |
| C | HOH3235 |
