3ABI
Crystal Structure of L-Lysine Dehydrogenase from Hyperthermophilic Archaeon Pyrococcus horikoshii
Replaces: 3A63Replaces: 2Z2VFunctional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004753 | molecular_function | saccharopine dehydrogenase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019878 | biological_process | lysine biosynthetic process via aminoadipic acid |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004753 | molecular_function | saccharopine dehydrogenase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019878 | biological_process | lysine biosynthetic process via aminoadipic acid |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2001 |
| Chain | Residue |
| A | GLY144 |
| A | GLY145 |
| A | TYR156 |
| A | TRP160 |
| A | GLU168 |
| A | THR224 |
| A | ARG226 |
| site_id | AC2 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE NAD A 1001 |
| Chain | Residue |
| A | ILE11 |
| A | ASP29 |
| A | VAL30 |
| A | ASN34 |
| A | VAL47 |
| A | ASP48 |
| A | ALA49 |
| A | ALA68 |
| A | LEU69 |
| A | PRO70 |
| A | GLY71 |
| A | LEU73 |
| A | VAL91 |
| A | SER92 |
| A | PHE93 |
| A | GLY117 |
| A | PHE118 |
| A | ALA119 |
| A | PRO120 |
| A | TRP160 |
| A | SER161 |
| A | ASP164 |
| A | THR299 |
| A | HOH2036 |
| A | GLY9 |
| A | ASN10 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2002 |
| Chain | Residue |
| A | VAL181 |
| B | GLU63 |
| B | LYS85 |
| B | VAL86 |
| B | ASP87 |
| site_id | AC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE NAD B 1002 |
| Chain | Residue |
| B | GLY9 |
| B | ASN10 |
| B | ILE11 |
| B | ASP29 |
| B | VAL30 |
| B | ASN34 |
| B | VAL47 |
| B | ASP48 |
| B | ALA49 |
| B | SER50 |
| B | ALA68 |
| B | LEU69 |
| B | PRO70 |
| B | GLY71 |
| B | LEU73 |
| B | VAL91 |
| B | SER92 |
| B | PHE93 |
| B | ALA119 |
| B | PRO120 |
| B | THR299 |
| B | HOH2025 |
