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3AA1

Crystal structure of Actin capping protein in complex with the Cp-binding motif derived from CKIP-1

Functional Information from GO Data
ChainGOidnamespacecontents
A0003779molecular_functionactin binding
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005886cellular_componentplasma membrane
A0008290cellular_componentF-actin capping protein complex
A0030018cellular_componentZ disc
A0030036biological_processactin cytoskeleton organization
A0030863cellular_componentcortical cytoskeleton
A0034329biological_processcell junction assembly
A0051015molecular_functionactin filament binding
A0051016biological_processbarbed-end actin filament capping
A0051693biological_processactin filament capping
A0071203cellular_componentWASH complex
B0003779molecular_functionactin binding
B0005737cellular_componentcytoplasm
B0008290cellular_componentF-actin capping protein complex
B0030036biological_processactin cytoskeleton organization
B0051016biological_processbarbed-end actin filament capping
Functional Information from PDB Data
site_idAC1
Number of Residues10
DetailsBINDING SITE FOR RESIDUE MES A 287
ChainResidue
APHE168
CALA151
AGLU200
AASP201
AHOH310
AHOH382
AHOH393
BARG14
BARG195
CLEU150

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE MES A 288
ChainResidue
AARG7
ALEU82
AARG86
ASER95
AGLN109
AHOH472
BLYS143
BHOH344
BHOH350

Functional Information from PROSITE/UniProt
site_idPS00231
Number of Residues6
DetailsF_ACTIN_CAPPING_BETA F-actin capping protein beta subunit signature. CDYNRD
ChainResidueDetails
BCYS62-ASP67

site_idPS00748
Number of Residues9
DetailsF_ACTIN_CAPPING_A_1 F-actin capping protein alpha subunit signature 1. VHYYEDGNV
ChainResidueDetails
AVAL196-VAL204

site_idPS00749
Number of Residues11
DetailsF_ACTIN_CAPPING_A_2 F-actin capping protein alpha subunit signature 2. KaLRRqLPVTR
ChainResidueDetails
ALYS256-ARG266

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsSITE: Interacts with capping protein
ChainResidueDetails
CARG155
CARG157

237423

PDB entries from 2025-06-11

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