3A8I

Crystal Structure of ET-EHred-5-CH3-THF complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004047	molecular_function	aminomethyltransferase activity
A	0005829	cellular_component	cytosol
A	0005960	cellular_component	glycine cleavage complex
A	0006546	biological_process	glycine catabolic process
A	0006730	biological_process	one-carbon metabolic process
A	0008483	molecular_function	transaminase activity
A	0016740	molecular_function	transferase activity
A	0019464	biological_process	glycine decarboxylation via glycine cleavage system
B	0004047	molecular_function	aminomethyltransferase activity
B	0005829	cellular_component	cytosol
B	0005960	cellular_component	glycine cleavage complex
B	0006546	biological_process	glycine catabolic process
B	0006730	biological_process	one-carbon metabolic process
B	0008483	molecular_function	transaminase activity
B	0016740	molecular_function	transferase activity
B	0019464	biological_process	glycine decarboxylation via glycine cleavage system
C	0004047	molecular_function	aminomethyltransferase activity
C	0005829	cellular_component	cytosol
C	0005960	cellular_component	glycine cleavage complex
C	0006546	biological_process	glycine catabolic process
C	0006730	biological_process	one-carbon metabolic process
C	0008483	molecular_function	transaminase activity
C	0016740	molecular_function	transferase activity
C	0019464	biological_process	glycine decarboxylation via glycine cleavage system
D	0004047	molecular_function	aminomethyltransferase activity
D	0005829	cellular_component	cytosol
D	0005960	cellular_component	glycine cleavage complex
D	0006546	biological_process	glycine catabolic process
D	0006730	biological_process	one-carbon metabolic process
D	0008483	molecular_function	transaminase activity
D	0016740	molecular_function	transferase activity
D	0019464	biological_process	glycine decarboxylation via glycine cleavage system
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005960	cellular_component	glycine cleavage complex
E	0006730	biological_process	one-carbon metabolic process
E	0019464	biological_process	glycine decarboxylation via glycine cleavage system
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005960	cellular_component	glycine cleavage complex
F	0006730	biological_process	one-carbon metabolic process
F	0019464	biological_process	glycine decarboxylation via glycine cleavage system

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE C2F A 401

Chain	Residue
A	MET51
A	GLU195
A	ARG223
A	MET232
A	TRP252
A	HOH621
A	HOH624
A	HOH749
A	HOH751
A	TYR84
A	ASP97
A	ILE99
A	TYR101
A	VAL111
A	ASN113
A	PHE173
A	TYR188

---

site_id	AC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE C2F B 401

Chain	Residue
B	MET51
B	TYR84
B	ASP97
B	TYR101
B	VAL111
B	ASN113
B	PHE173
B	TYR188
B	GLU195
B	ARG223
B	MET232
B	TRP252
B	ARG357
B	HOH651
B	HOH655
B	HOH828
B	HOH837

---

site_id	AC3
Number of Residues	17
Details	BINDING SITE FOR RESIDUE C2F C 401

Chain	Residue
C	TYR84
C	ASP97
C	ILE99
C	TYR101
C	VAL111
C	ASN113
C	PHE173
C	GLY187
C	TYR188
C	GLU195
C	ARG223
C	MET232
C	TRP252
C	PO4501
C	HOH627
C	HOH669
C	HOH840

---

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PO4 C 501

Chain	Residue
C	HIS50
C	ASN113
C	SER114
C	ARG223
C	LEU234
C	C2F401
C	HOH762
C	HOH815
C	HOH845

---

site_id	AC5
Number of Residues	15
Details	BINDING SITE FOR RESIDUE C2F D 401

Chain	Residue
D	TYR84
D	ASP97
D	ILE99
D	TYR101
D	VAL111
D	ASN113
D	GLY187
D	TYR188
D	GLU195
D	ARG223
D	MET232
D	TRP252
D	PO4501
D	HOH744
D	HOH803

---

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PO4 D 501

Chain	Residue
D	PHE20
D	HIS50
D	ASN113
D	SER114
D	ARG223
D	LEU234
D	C2F401
D	HOH764
D	HOH794

---

Functional Information from PROSITE/UniProt

site_id	PS00189
Number of Residues	30
Details	LIPOYL 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. GatVsagDDCavAESvKAAsdIyapvsGeI

Chain	Residue	Details
E	GLY48-ILE77

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"N6-lipoyllysine","evidences":[{"source":"HAMAP-Rule","id":"MF_00272","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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