3A8I
Crystal Structure of ET-EHred-5-CH3-THF complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004047 | molecular_function | aminomethyltransferase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0005960 | cellular_component | glycine cleavage complex |
| A | 0006546 | biological_process | glycine catabolic process |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0019464 | biological_process | glycine decarboxylation via glycine cleavage system |
| B | 0004047 | molecular_function | aminomethyltransferase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0005960 | cellular_component | glycine cleavage complex |
| B | 0006546 | biological_process | glycine catabolic process |
| B | 0006730 | biological_process | one-carbon metabolic process |
| B | 0019464 | biological_process | glycine decarboxylation via glycine cleavage system |
| C | 0004047 | molecular_function | aminomethyltransferase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0005960 | cellular_component | glycine cleavage complex |
| C | 0006546 | biological_process | glycine catabolic process |
| C | 0006730 | biological_process | one-carbon metabolic process |
| C | 0019464 | biological_process | glycine decarboxylation via glycine cleavage system |
| D | 0004047 | molecular_function | aminomethyltransferase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0005960 | cellular_component | glycine cleavage complex |
| D | 0006546 | biological_process | glycine catabolic process |
| D | 0006730 | biological_process | one-carbon metabolic process |
| D | 0019464 | biological_process | glycine decarboxylation via glycine cleavage system |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0005960 | cellular_component | glycine cleavage complex |
| E | 0006730 | biological_process | one-carbon metabolic process |
| E | 0019464 | biological_process | glycine decarboxylation via glycine cleavage system |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0005960 | cellular_component | glycine cleavage complex |
| F | 0006730 | biological_process | one-carbon metabolic process |
| F | 0019464 | biological_process | glycine decarboxylation via glycine cleavage system |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE C2F A 401 |
| Chain | Residue |
| A | MET51 |
| A | GLU195 |
| A | ARG223 |
| A | MET232 |
| A | TRP252 |
| A | HOH621 |
| A | HOH624 |
| A | HOH749 |
| A | HOH751 |
| A | TYR84 |
| A | ASP97 |
| A | ILE99 |
| A | TYR101 |
| A | VAL111 |
| A | ASN113 |
| A | PHE173 |
| A | TYR188 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE C2F B 401 |
| Chain | Residue |
| B | MET51 |
| B | TYR84 |
| B | ASP97 |
| B | TYR101 |
| B | VAL111 |
| B | ASN113 |
| B | PHE173 |
| B | TYR188 |
| B | GLU195 |
| B | ARG223 |
| B | MET232 |
| B | TRP252 |
| B | ARG357 |
| B | HOH651 |
| B | HOH655 |
| B | HOH828 |
| B | HOH837 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE C2F C 401 |
| Chain | Residue |
| C | TYR84 |
| C | ASP97 |
| C | ILE99 |
| C | TYR101 |
| C | VAL111 |
| C | ASN113 |
| C | PHE173 |
| C | GLY187 |
| C | TYR188 |
| C | GLU195 |
| C | ARG223 |
| C | MET232 |
| C | TRP252 |
| C | PO4501 |
| C | HOH627 |
| C | HOH669 |
| C | HOH840 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 C 501 |
| Chain | Residue |
| C | HIS50 |
| C | ASN113 |
| C | SER114 |
| C | ARG223 |
| C | LEU234 |
| C | C2F401 |
| C | HOH762 |
| C | HOH815 |
| C | HOH845 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE C2F D 401 |
| Chain | Residue |
| D | TYR84 |
| D | ASP97 |
| D | ILE99 |
| D | TYR101 |
| D | VAL111 |
| D | ASN113 |
| D | GLY187 |
| D | TYR188 |
| D | GLU195 |
| D | ARG223 |
| D | MET232 |
| D | TRP252 |
| D | PO4501 |
| D | HOH744 |
| D | HOH803 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 D 501 |
| Chain | Residue |
| D | PHE20 |
| D | HIS50 |
| D | ASN113 |
| D | SER114 |
| D | ARG223 |
| D | LEU234 |
| D | C2F401 |
| D | HOH764 |
| D | HOH794 |
Functional Information from PROSITE/UniProt
| site_id | PS00189 |
| Number of Residues | 30 |
| Details | LIPOYL 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. GatVsagDDCavAESvKAAsdIyapvsGeI |
| Chain | Residue | Details |
| E | GLY48-ILE77 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-lipoyllysine","evidences":[{"source":"HAMAP-Rule","id":"MF_00272","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
