3A7J
Human MST3 kinase in complex with MnADP
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE ADP A 500 |
| Chain | Residue |
| A | ILE30 |
| A | LEU102 |
| A | ASN149 |
| A | LEU151 |
| A | ASP162 |
| A | HOH344 |
| A | MN501 |
| A | MN502 |
| A | HOH520 |
| A | HOH544 |
| A | HOH588 |
| A | GLY33 |
| A | HOH589 |
| A | HOH591 |
| A | HOH593 |
| A | SER34 |
| A | PHE35 |
| A | VAL38 |
| A | ALA51 |
| A | LYS53 |
| A | MET99 |
| A | GLU100 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 501 |
| Chain | Residue |
| A | ASN149 |
| A | ASP162 |
| A | HOH444 |
| A | ADP500 |
| A | HOH588 |
| A | HOH593 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 502 |
| Chain | Residue |
| A | ASP162 |
| A | HOH344 |
| A | ADP500 |
| A | HOH521 |
| A | HOH633 |
| A | HOH635 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGKGSFGEVFkGidnrtqkv..........VAIK |
| Chain | Residue | Details |
| A | ILE30-LYS53 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI2 |
| Number of Residues | 13 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Motif: {"description":"Bipartite nuclear localization signal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine; by autocatalysis","evidences":[{"source":"PubMed","id":"17046825","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19604147","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20124694","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
