3A74
Lysyl-tRNA synthetase from Bacillus stearothermophilus complexed with Diadenosine Tetraphosphate (AP4A)
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000049 | molecular_function | tRNA binding |
A | 0000166 | molecular_function | nucleotide binding |
A | 0000287 | molecular_function | magnesium ion binding |
A | 0003676 | molecular_function | nucleic acid binding |
A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
A | 0004824 | molecular_function | lysine-tRNA ligase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006412 | biological_process | translation |
A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
A | 0006430 | biological_process | lysyl-tRNA aminoacylation |
A | 0016740 | molecular_function | transferase activity |
A | 0046872 | molecular_function | metal ion binding |
B | 0000049 | molecular_function | tRNA binding |
B | 0000166 | molecular_function | nucleotide binding |
B | 0000287 | molecular_function | magnesium ion binding |
B | 0003676 | molecular_function | nucleic acid binding |
B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
B | 0004824 | molecular_function | lysine-tRNA ligase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0006412 | biological_process | translation |
B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
B | 0006430 | biological_process | lysyl-tRNA aminoacylation |
B | 0016740 | molecular_function | transferase activity |
B | 0046872 | molecular_function | metal ion binding |
C | 0000049 | molecular_function | tRNA binding |
C | 0000166 | molecular_function | nucleotide binding |
C | 0000287 | molecular_function | magnesium ion binding |
C | 0003676 | molecular_function | nucleic acid binding |
C | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
C | 0004824 | molecular_function | lysine-tRNA ligase activity |
C | 0005524 | molecular_function | ATP binding |
C | 0005737 | cellular_component | cytoplasm |
C | 0005829 | cellular_component | cytosol |
C | 0006412 | biological_process | translation |
C | 0006418 | biological_process | tRNA aminoacylation for protein translation |
C | 0006430 | biological_process | lysyl-tRNA aminoacylation |
C | 0016740 | molecular_function | transferase activity |
C | 0046872 | molecular_function | metal ion binding |
D | 0000049 | molecular_function | tRNA binding |
D | 0000166 | molecular_function | nucleotide binding |
D | 0000287 | molecular_function | magnesium ion binding |
D | 0003676 | molecular_function | nucleic acid binding |
D | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
D | 0004824 | molecular_function | lysine-tRNA ligase activity |
D | 0005524 | molecular_function | ATP binding |
D | 0005737 | cellular_component | cytoplasm |
D | 0005829 | cellular_component | cytosol |
D | 0006412 | biological_process | translation |
D | 0006418 | biological_process | tRNA aminoacylation for protein translation |
D | 0006430 | biological_process | lysyl-tRNA aminoacylation |
D | 0016740 | molecular_function | transferase activity |
D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 30 |
Details | BINDING SITE FOR RESIDUE B4P A 494 |
Chain | Residue |
A | ARG253 |
A | GLU366 |
A | GLU370 |
A | GLU411 |
A | HIS412 |
A | ASN414 |
A | GLY467 |
A | ARG470 |
A | ILE481 |
A | LYN495 |
A | HOH508 |
A | GLU255 |
A | HOH511 |
A | HOH543 |
A | HOH747 |
A | HOH802 |
A | HOH885 |
A | HOH914 |
A | MG1000 |
A | MG1001 |
A | MG1002 |
A | HOH1291 |
A | GLY256 |
A | HOH1300 |
A | SER258 |
A | ARG260 |
A | HIS261 |
A | ASN262 |
A | PHE265 |
A | MET267 |
site_id | AC2 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE LYN A 495 |
Chain | Residue |
A | GLY207 |
A | ALA229 |
A | GLU231 |
A | ARG253 |
A | MET267 |
A | GLU269 |
A | TYR271 |
A | ASN414 |
A | PHE416 |
A | GLU418 |
A | B4P494 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG A 1000 |
Chain | Residue |
A | GLU404 |
A | GLU411 |
A | ALA413 |
A | ASN414 |
A | B4P494 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG A 1001 |
Chain | Residue |
A | B4P494 |
A | HOH508 |
A | HOH543 |
A | HOH802 |
A | HOH1291 |
site_id | AC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG A 1002 |
Chain | Residue |
A | GLU404 |
A | GLU411 |
A | B4P494 |
A | HOH1300 |
site_id | AC6 |
Number of Residues | 30 |
Details | BINDING SITE FOR RESIDUE B4P B 494 |
Chain | Residue |
B | ARG253 |
B | GLU255 |
B | GLY256 |
B | SER258 |
B | ARG260 |
B | HIS261 |
B | ASN262 |
B | PHE265 |
B | MET267 |
B | GLU366 |
B | GLU370 |
B | GLU411 |
B | HIS412 |
B | ALA413 |
B | ASN414 |
B | GLY467 |
B | ARG470 |
B | ILE481 |
B | LYN495 |
B | HOH502 |
B | HOH580 |
B | HOH864 |
B | HOH866 |
B | HOH868 |
B | HOH870 |
B | MG1100 |
B | MG1101 |
B | MG1102 |
B | HOH1206 |
C | GLN438 |
site_id | AC7 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE LYN B 495 |
Chain | Residue |
B | GLY207 |
B | ALA208 |
B | GLU231 |
B | ARG253 |
B | MET267 |
B | GLU269 |
B | TYR271 |
B | ASN414 |
B | PHE416 |
B | GLU418 |
B | B4P494 |
site_id | AC8 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG B 1100 |
Chain | Residue |
B | B4P494 |
B | HOH1206 |
B | GLU404 |
B | GLU411 |
B | ASN414 |
site_id | AC9 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG B 1101 |
Chain | Residue |
B | B4P494 |
B | HOH580 |
B | HOH864 |
B | HOH865 |
B | HOH868 |
site_id | BC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG B 1102 |
Chain | Residue |
B | GLU404 |
B | GLU411 |
B | B4P494 |
B | HOH1206 |
site_id | BC2 |
Number of Residues | 31 |
Details | BINDING SITE FOR RESIDUE B4P C 494 |
Chain | Residue |
C | ARG253 |
C | GLU255 |
C | GLY256 |
C | SER258 |
C | ARG260 |
C | HIS261 |
C | ASN262 |
C | PHE265 |
C | MET267 |
C | GLU366 |
C | GLU370 |
C | GLU411 |
C | HIS412 |
C | ASN414 |
C | GLY467 |
C | ARG470 |
C | ILE481 |
C | LYN495 |
C | HOH507 |
C | HOH509 |
C | HOH723 |
C | HOH819 |
C | HOH915 |
C | HOH917 |
C | HOH925 |
C | MG1200 |
C | MG1201 |
C | MG1202 |
C | HOH1302 |
C | HOH1303 |
C | HOH1304 |
site_id | BC3 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE LYN C 495 |
Chain | Residue |
C | GLY207 |
C | ALA229 |
C | GLU231 |
C | ARG253 |
C | MET267 |
C | GLU269 |
C | TYR271 |
C | ASN414 |
C | PHE416 |
C | GLU418 |
C | B4P494 |
site_id | BC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG C 1200 |
Chain | Residue |
C | GLU404 |
C | GLU411 |
C | ALA413 |
C | ASN414 |
C | B4P494 |
site_id | BC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG C 1201 |
Chain | Residue |
C | B4P494 |
C | HOH509 |
C | HOH819 |
C | HOH915 |
C | HOH917 |
site_id | BC6 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG C 1202 |
Chain | Residue |
C | GLU404 |
C | GLU411 |
C | B4P494 |
C | HOH1302 |
site_id | BC7 |
Number of Residues | 29 |
Details | BINDING SITE FOR RESIDUE B4P D 494 |
Chain | Residue |
A | GLN438 |
D | ARG253 |
D | GLU255 |
D | GLY256 |
D | ARG260 |
D | HIS261 |
D | ASN262 |
D | PHE265 |
D | MET267 |
D | GLU366 |
D | GLU370 |
D | GLU411 |
D | HIS412 |
D | ALA413 |
D | ASN414 |
D | GLY467 |
D | ARG470 |
D | ILE481 |
D | LYN495 |
D | HOH501 |
D | HOH596 |
D | HOH851 |
D | HOH853 |
D | HOH855 |
D | HOH1164 |
D | MG1300 |
D | MG1301 |
D | MG1302 |
D | HOH1307 |
site_id | BC8 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE LYN D 495 |
Chain | Residue |
D | GLY207 |
D | ALA208 |
D | GLU231 |
D | ARG253 |
D | MET267 |
D | GLU269 |
D | TYR271 |
D | ASN414 |
D | PHE416 |
D | GLU418 |
D | B4P494 |
site_id | BC9 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG D 1300 |
Chain | Residue |
D | GLU404 |
D | GLU411 |
D | ALA413 |
D | ASN414 |
D | B4P494 |
D | HOH1305 |
site_id | CC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG D 1301 |
Chain | Residue |
D | B4P494 |
D | HOH596 |
D | HOH851 |
D | HOH852 |
D | HOH853 |
site_id | CC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG D 1302 |
Chain | Residue |
D | GLU404 |
D | GLU411 |
D | B4P494 |
D | HOH1307 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 8 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | GLU404 | |
A | GLU411 | |
B | GLU404 | |
B | GLU411 | |
C | GLU404 | |
C | GLU411 | |
D | GLU404 | |
D | GLU411 |