3A6V
Crystal structure of the MutT protein in MN(II) bound holo form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0006203 | biological_process | dGTP catabolic process |
| A | 0006260 | biological_process | DNA replication |
| A | 0006281 | biological_process | DNA repair |
| A | 0006289 | biological_process | nucleotide-excision repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008413 | molecular_function | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0035539 | molecular_function | 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity |
| A | 0044715 | molecular_function | 8-oxo-dGDP phosphatase activity |
| A | 0044716 | molecular_function | 8-oxo-GDP phosphatase activity |
| A | 0046067 | biological_process | dGDP catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047693 | molecular_function | ATP diphosphatase activity |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0006203 | biological_process | dGTP catabolic process |
| B | 0006260 | biological_process | DNA replication |
| B | 0006281 | biological_process | DNA repair |
| B | 0006289 | biological_process | nucleotide-excision repair |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008413 | molecular_function | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0030145 | molecular_function | manganese ion binding |
| B | 0035539 | molecular_function | 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity |
| B | 0044715 | molecular_function | 8-oxo-dGDP phosphatase activity |
| B | 0044716 | molecular_function | 8-oxo-GDP phosphatase activity |
| B | 0046067 | biological_process | dGDP catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047693 | molecular_function | ATP diphosphatase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 1003 |
| Chain | Residue |
| A | GLU53 |
| A | GLU57 |
| A | HOH132 |
| A | HOH133 |
| B | ASP77 |
| B | HOH132 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 1004 |
| Chain | Residue |
| B | HOH132 |
| B | HOH138 |
| B | TLA2001 |
| A | GLU53 |
| A | HOH131 |
| A | HOH134 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1005 |
| Chain | Residue |
| A | GLY37 |
| A | GLU57 |
| A | HOH153 |
| B | ASP77 |
| B | HOH186 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE TLA A 2002 |
| Chain | Residue |
| A | LYS39 |
| A | ARG78 |
| A | HOH149 |
| B | LYS39 |
| B | ARG78 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE TLA A 2003 |
| Chain | Residue |
| A | LYS2 |
| A | ARG78 |
| A | HOH138 |
| B | GLU41 |
| B | HOH134 |
| B | HOH135 |
| B | HOH150 |
| B | MN1002 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 1001 |
| Chain | Residue |
| A | ASP77 |
| A | HOH136 |
| B | GLU53 |
| B | GLU57 |
| B | HOH137 |
| B | HOH181 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 1002 |
| Chain | Residue |
| A | HOH136 |
| A | HOH138 |
| A | TLA2003 |
| B | GLU53 |
| B | HOH134 |
| B | HOH135 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 1006 |
| Chain | Residue |
| A | ASP77 |
| A | HOH163 |
| B | GLY37 |
| B | GLU57 |
| B | HOH140 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE TLA B 2001 |
| Chain | Residue |
| A | GLU41 |
| A | HOH131 |
| A | HOH134 |
| A | HOH158 |
| A | HOH191 |
| A | MN1004 |
| B | LYS2 |
| B | ARG78 |
| B | HOH132 |
| B | HOH138 |
| B | HOH142 |
Functional Information from PROSITE/UniProt
| site_id | PS00893 |
| Number of Residues | 22 |
| Details | NUDIX_BOX Nudix box signature. GkiemgEtpeqAVvRELqEEvG |
| Chain | Residue | Details |
| A | GLY38-GLY59 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 42 |
| Details | Motif: {"description":"Nudix box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00794","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19864691","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19864691","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12939141","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"19864691","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
