Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE GOL B 803 |
| Chain | Residue |
| A | GLN18 |
| B | GLY168 |
| B | HOH1477 |
| B | HOH1643 |
| B | HOH1644 |
| B | HOH1645 |
| B | HOH1646 |
| A | MET36 |
| A | SER37 |
| B | THR112 |
| B | ILE113 |
| B | LYS114 |
| B | GLU165 |
| B | ILE166 |
| B | ALA167 |
| site_id | AC2 |
| Number of Residues | 42 |
| Details | BINDING SITE FOR RESIDUE KNJ B 999 |
| Chain | Residue |
| A | LEU23 |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | VAL32 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | VAL82 |
| A | ILE84 |
| A | HOH1039 |
| A | HOH1433 |
| A | HOH1445 |
| A | HOH1598 |
| A | HOH1638 |
| A | HOH1639 |
| A | HOH1648 |
| A | HOH1657 |
| B | LEU123 |
| B | ASP125 |
| B | GLY127 |
| B | ALA128 |
| B | ASP129 |
| B | ASP130 |
| B | VAL132 |
| B | ILE147 |
| B | GLY148 |
| B | GLY149 |
| B | ILE150 |
| B | PRO181 |
| B | ILE184 |
| B | HOH1079 |
| B | HOH1095 |
| B | HOH1472 |
| B | HOH1568 |
| B | HOH1571 |
| B | HOH1595 |
| B | HOH1596 |
| B | HOH1654 |
| B | HOH1655 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Region: {"description":"Dimerization of protease","evidences":[{"source":"UniProtKB","id":"P04585","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"For protease activity; shared with dimeric partner","evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
