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3A01

Crystal structure of Aristaless and Clawless homeodomains bound to DNA

Functional Information from GO Data
ChainGOidnamespacecontents
A0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
A0003677molecular_functionDNA binding
A0003700molecular_functionDNA-binding transcription factor activity
A0006355biological_processregulation of DNA-templated transcription
B0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
B0003677molecular_functionDNA binding
B0006355biological_processregulation of DNA-templated transcription
E0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
E0003677molecular_functionDNA binding
E0003700molecular_functionDNA-binding transcription factor activity
E0006355biological_processregulation of DNA-templated transcription
F0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
F0003677molecular_functionDNA binding
F0006355biological_processregulation of DNA-templated transcription
Functional Information from PROSITE/UniProt
site_idPS00027
Number of Residues24
DetailsHOMEOBOX_1 'Homeobox' domain signature. LAmkIgLTeaRIQVWFqNrrakwR
ChainResidueDetails
BLEU118-ARG141
ALEU218-ARG241

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues118
DetailsDNA_BIND: Homeobox => ECO:0000255|PROSITE-ProRule:PRU00108
ChainResidueDetails
BGLN85-GLU144
FGLN85-GLU144

237735

PDB entries from 2025-06-18

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