39CB
perdeuterated M379A tyrosine phenol lyase apoenzyme
Functional Information from PROSITE/UniProt
| site_id | PS00853 |
| Number of Residues | 19 |
| Details | BETA_ELIM_LYASE Beta-eliminating lyases pyridoxal-phosphate attachment site. YaDgctMSGKKDcLVnIGG |
| Chain | Residue | Details |
| A | TYR247-GLY265 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine"} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 933 |
| Chain | Residue | Details |
| A | TYR71 | proton acceptor, proton donor |
| A | ASP214 | electrostatic stabiliser |
| A | LYS257 | covalently attached, electron pair acceptor, electron pair donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| A | ARG381 | electrostatic stabiliser |
| A | PHE448 | electrostatic stabiliser, ground state destabiliser |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 933 |
| Chain | Residue | Details |
| B | TYR71 | proton acceptor, proton donor |
| B | ASP214 | electrostatic stabiliser |
| B | LYS257 | covalently attached, electron pair acceptor, electron pair donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| B | ARG381 | electrostatic stabiliser |
| B | PHE448 | electrostatic stabiliser, ground state destabiliser |
