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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

38HT

Cryo-EM structure of apo-pSTAT1

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues194
DetailsDomain: {"description":"SH2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00191","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues362
DetailsCoiled coil: {"evidences":[{"source":"PubMed","id":"9630226","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues12
DetailsModified residue: {"description":"N6-methyllysine","evidences":[{"source":"PubMed","id":"28753426","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues4
DetailsModified residue: {"description":"ADP-ribosyl glutamic acid; by PARP14","evidences":[{"source":"PubMed","id":"27796300","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues2
DetailsModified residue: {"description":"Phosphotyrosine; by JAK1, JAK2 or TYK2","evidences":[{"source":"PubMed","id":"17561467","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19088846","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21135090","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22065572","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26479788","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27796300","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28753426","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38621137","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7657660","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues2
DetailsModified residue: {"description":"Phosphoserine; by IKKE","evidences":[{"source":"PubMed","id":"22065572","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues4
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

262513

PDB entries from 2026-11-04

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